Projects per year
Personal profile
Research interests
Immunology, glycosylation, dendritic cells, glycan-binding receptors, anti-tumor immunity
Specialisation
Cellular glycosylation is a highly dynamic process that alters upon activation, inflammation, and oncogenic transformation. Although it has been known for decades that cell surface glycans are highly diverse, it is still unclear how glycan heterogeneity is established and how this impacts tumor cell biology and immune cell recognition.
During my cum laude PhD and postdoctoral years I studied the impact of glycosylation and glycan-binding receptors on dendritic cell biology and specialized in the field of glyco-immunology. I obtained a prestigious NWO-VENI grant in 2010 that allowed me to dissect the signaling properties of glycan-binding receptors. With grants from the Dutch Cancer Society, Cancer Center Amsterdam and European Marie Curie ITN network and NWO-ASPASIA, I have established her own independent research group that aims to unravel how tumor glycans affect tumor progression, metastasis and anti-tumor immunity.
Fingerprint
Dive into the research topics where Sandra van Vliet is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 3 Finished
-
GLYCOTARGET. A NEW FRONTIER IN EXTRACELLULAR VESICLE-MEDIATED CANCER IMMUNOMODULATION<br>
Reis, C. A. C. A. (Principal investigator), Oliveira, M. J. C. M. J. C. (CoPI), Henrique, R. M. F. R. M. F. (CoPI), De Sena Bastos Gomes, C. C. (CoPI), Osorio, H. A. C. P. H. A. C. P. (CoPI), Gomes, J. N. C. J. N. C. (CoPI), Jerónimo, C. C. (CoPI), De Magalhães, A. M. R. L. A. M. R. L. (CoPI), Lyden, D. D. (CoPI), Freitas, D. S. P. D. S. P. (CoPI), De Oliveira Duarte, H. M. F. H. M. F. (CoPI), Mesquita, I. M. M. I. M. M. (CoPI), De Sousa Grácio Fernandes Rodrigues, J. J. (CoPI), van Vliet, S. (CoPI), De Fátima Gärtner, M. M. (CoPI), De Sousa Martins, &. M. &. M. (CoPI) & Bouza, L. S. L. S. (CoPI)
Fundação para a Ciência e a Tecnologia
01/01/2022 → 31/12/2024
Project: Research
-
Targeting human macrophage galactose C-type lectin towards the development of innovative and alternative cancer therapies
Marcelo, F. F. (Principal investigator), Da Silva Cabrita, E. J. E. J. (CoPI), Coelho, H. M. N. H. M. N. (CoPI), Reis, C. A. C. A. (CoPI), De Sá Palma, M. A. M. A. (CoPI), Diniz, A. A. (CoPI), Corzana, F. F. (CoPI), van Vliet, S. (CoPI), De Campos Grosso, A. S. A. S. (CoPI) & Garcia-martin, F. M. F. M. (CoPI)
Fundação para a Ciência e a Tecnologia
01/03/2021 → 29/02/2024
Project: Research
-
Advances in MUC1 Glycan Cancer Antigens: From structure to function in the fight against cancer
De Sá Palma, M. A. M. A. (Principal investigator), Marcelo, F. F. (CoPI), Coelho, H. M. N. H. M. N. (CoPI), Da Silva Dias, J. J. (CoPI), Da Silva, Z. M. C. Z. M. C. (CoPI), Da Silva Cabrita, E. J. E. J. (CoPI), Videira, P. A. Q. P. A. Q. (CoPI), Reis, C. A. C. A. (CoPI), De Oliveira Ribeiro, D. D. (CoPI), Correia, V. G. V. G. (CoPI), Hurtado-guerrero, R. R. (CoPI), Wandall, H. H. H. H. (CoPI), Diniz, A. A. (CoPI), van Vliet, S. (CoPI) & Osorio, H. A. C. P. H. A. C. P. (CoPI)
Fundação para a Ciência e a Tecnologia
01/10/2018 → 30/09/2022
Project: Research
-
Integration of Stromal Cells and Hydrogel Below Epithelium Results in Optimal Barrier Properties of Small Intestine Organoid Models
Asal, M., Thon, M., Waaijman, T., Bontkes, H. J., van Vliet, S. J., Mebius, R. E. & Gibbs, S., 1 Dec 2024, In: Biomedicines. 12, 12, 2913.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Limited impact of cancer-derived gangliosides on anti-tumor immunity in colorectal cancer
van der Haar Àvila, I., Zhang, T., Lorrain, V., de Bruin, F., Spreij, T., Nakayama, H., Iwabuchi, K., García-Vallejo, J. J., Wuhrer, M., van Kooyk, Y. & van Vliet, S. J., 1 Jul 2024, In: Glycobiology. 34, 7, cwae036.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions
Boelaars, K., Rodriguez, E., Huinen, Z. R., Liu, C., Wang, D., Springer, B. O., Olesek, K., Goossens-Kruijssen, L., van Ee, T., Lindijer, D., Tak, W., de Haas, A., Wehry, L., Nugteren-Boogaard, J. P., Mikula, A., de Winde, C. M., Mebius, R. E., Tuveson, D. A., Giovannetti, E. & Bijlsma, M. F. & 3 others, , 1 Dec 2024, In: Communications Biology. 7, 1, p. 430 430.Research output: Contribution to journal › Article › Academic › peer-review
Open Access14 Citations (Scopus) -
Sialic acid–modified der p 2 allergen exerts immunomodulatory effects on human PBMCs
Keumatio Doungtsop, B.-C., Nardini, E., Kalay, H., Versteeg, S. A., Lübbers, J., van Barneveld, G., Li, E. R. J., van Vliet, S. J., van Ree, R., de Jong, E. C. & van Kooyk, Y., 1 Feb 2024, In: Journal of Allergy and Clinical Immunology: Global. 3, 1, p. 100193 100193.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
The pleiotropic CLEC10A: implications for harnessing this receptor in the tumor microenvironment
van der Meijs, N. L., Travecedo, M. A., Marcelo, F. & van Vliet, S. J., 2024, In: Expert opinion on therapeutic targets. 28, 7, p. 601-612 12 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access2 Citations (Scopus)
-
European Macrophage and Dendritic Cell Society
van Vliet, S. (Participant)
18 Oct 2023 → 20 Oct 2023Activity: Participating in or organising an event › participating
-
TUMOR-ASSOCIATED GLYCAN STRUCTURES: FRIEND OR FOE IN IMMUNITY TO CANCER?
van Vliet, S. (Speaker)
28 Sept 2023Activity: Talk or presentation › Invited talk › Academic
-
CCA retreat 2023
van Vliet, S. (Participant)
6 Jul 2023 → 7 Jul 2023Activity: Participating in or organising an event › participating
-
AII annual symposium
van Vliet, S. (Participant)
22 Jun 2023Activity: Participating in or organising an event › participating
-
TUMOR-ASSOCIATED GLYCAN STRUCTURES: FRIEND OR FOE IN IMMUNITY TO CANCER?
van Vliet, S. (Speaker)
14 Jun 2023 → 16 Jun 2023Activity: Talk or presentation › Invited talk › Academic
Prizes
Press/Media
-
Journal club for "Antibuddies - Science communication & immunology"
18/09/2021
1 Media contribution
Press/Media: publicengagement