Research output per year
Research output per year
Personal profile
Research interests
My translational immunology research evolves around the overarching theme “The molecular regulation of inflammation”. Projects integrate basic immunological experiments, novel techniques and sampling of multiple tissues (translational medicine). Ultimate goals include development of new treatment strategies targeting (non-canonical) NF-κB signaling for immune-mediated inflammatory diseases (IMIDs).
Keywords: signal transduction pathways (i.e. NF-κB signaling), AIRE, rheumatoid arthritis, (rare) systemic autoimmune diseases including vasculitis, synovial inflammation, lymph node biology, immune cells, stromal cells, angiogenesis, gene therapy.
Participation in (inter)national consortia: ImmuneImage, DC4Balance, Joint Biology Consortium (Harvard/MIT), ARCAID, the Human Cell Atlas project.
Active member of various EULAR taskforces, EULAR synovitis study group (ESSG), and Standing Committee on Investigative Rheumatology (ESCIR).
Specialisation
Internal Medicine-Rheumatology
Education/Academic qualification
Hoogleraar Reumatologie, in het bijzonder de moleculaire basis en behandeling van autoimmuunziekten, Amsterdam UMC - University of Amsterdam
30 Aug 2022 → …
Award Date: 30 Aug 2022
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting of proangiogenic signalling pathways in chronic inflammation
Tas, S. W., Maracle, C. X., Balogh, E. & Szekanecz, Z., 2016, In: Nature reviews. Rheumatology. 12, 2, p. 111-122Research output: Contribution to journal › Review article › Academic › peer-review
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Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-κB-Inducing Kinase-Positive Endothelial Cells as Central Players
Noort, A. R., van Zoest, K. P. M., van Baarsen, L. G., Maracle, C. X., Helder, B., Papazian, N., Romera-Hernandez, M., Tak, P. P., Cupedo, T. & Tas, S. W., 2015, In: American journal of pathology. 185, 7, p. 1935-1943Research output: Contribution to journal › Article › Academic › peer-review
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NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis
Noort, A. R., van Zoest, K. P. M., Weijers, E. M., Koolwijk, P., Maracle, C. X., Novack, D. V., Siemerink, M. J., Schlingemann, R. O., Tak, P. P. & Tas, S. W., 2014, In: Journal of pathology. 234, 3, p. 375-385Research output: Contribution to journal › Article › Academic › peer-review
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Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?
Noort, A. R., Tak, P. P. & Tas, S. W., 2015, In: Arthritis research & therapy. 17, 1, p. 15Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile -
Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study
Maijer, K. I., Noort, A. R., de Hair, M. J. H., van der Leij, C., van Zoest, K. P. M., Choi, I. Y., Gerlag, D. M., Maas, M., Tak, P. P. & Tas, S. W., 2015, In: Journal of rheumatology. 42, 9, p. 1573-1581Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile