Projects per year
Personal profile
Research interests
As a Hepato-Pancreatico-Biliary (HPB) Surgeon, my research focusses on multimodality molecular imaging to allow integration of diagnostic and intraoperative imaging in patients suffering from tumors in the liver, pancreas and biliary tract.
After obtaining my medical degree in 2006, I spent three years at Stanford University studying molecular imaging of embryonic stem cell transplantation, for which I received a PhD degree at the Leiden University (Prof. dr. J.F. Hamming, Prof. Dr. R.C. Robbins and Dr. J.C. Wu). This research was supported by grants from the European Society for Organ Transplantation and the Fulbright Foundation. Upon returning to The Netherlands, I started Surgery Residency at the Leiden University Medical Center and the Bronovo Hospital in The Hague. I became interested in surgical oncology, specifically hepatobiliary and pancreatic cancers and got the opportunity to join the Image-Guided Surgery research group (Prof. Dr. C. van de Velde, Dr. A.L. Vahrmeijer) at the LUMC. In 2011, I worked full time for a year as a post-doc. During that time, my first paper as a senior author was published. In 2010, I co-founded the Lisa Waller Hayes Foundation (www.lwhfoundation.com). This foundation is dedicated to advance scientific research in the field of pancreatic cancer and to provide a platform of information to patients and their families. After finishing training as a surgical oncologist in July 2015, I did a 2-year fellowship in HPB surgery at the LUMC. During that time, I instigated renewed collaboration with Stanford University’s Multimodality Molecular Imaging Lab (Prof. Dr. S.S. Gambhir) and gathered funding from several sources to allow PhD and graduate students to spent 1-2 years at Stanford. Joint projects primarily focus on the development and clinical translation of molecularly-targeted, tumor-specific imaging agents. In August of 2018, I was appointed staff member in HPB surgery at Amsterdam UMC. In that same year, I was awarded a Young Investigator Grant by the KWF, which has allowed me to form my own research group. My first PhD candidate graduated in November of 2018. Currently, I am the supervisor (co-promotor) of 4 PhD candidates and several graduate students at Amsterdam UMC and the LUMC. Recently, I was awarded a grant by the Cancer Center Amsterdam.
Being appointed as a surgeon in both the AMC and VUmc locations, I play an active role in the alliance, specifically for the HPB department. By merging researchers and clinicians from the different biomedical imaging groups (CCA, Imaging Center), as well as the Amsterdam Skills Center (ASC), I see a great future ahead for translational molecularly targeted imaging research and implementation at Amsterdam UMC.
Specialisation
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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LIVEROBOT: Liverobot
Swijnenburg, R.-J. (Principal investigator)
Intuitive Surgical Operations, Inc.
01/11/2022 → 01/11/2026
Project: Research
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PANSCAN - 2 (restant VUMC): Clinical Translation of integrin avb6-Targeted Molecular Imaging for pancreatic Cancer Detection - PANSCAN
Swijnenburg, R.-J. (Principal investigator)
Bureau Stichting Cancer Center Amsterdam
23/02/2021 → 30/06/2026
Project: Research
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Speakerfee 2020 - 2025 R. Swijnenburg: Speakerfee 2020 - 2025
Swijnenburg, R.-J. (Principal investigator)
06/07/2020 → 05/07/2025
Project: Research
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PANSCAN: Clinical Translation of integrin avb6-Targeted Molecular Imaging for pancreatic Cancer Detection - PANSCAN
Swijnenburg, R.-J. (Principal investigator)
01/05/2018 → 30/04/2026
Project: Research
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2022 Research Fellowship Cholangiocarcinoma: Clinical translation of Integrin avß6-targeted molecular imaging for cholangiocarcinoma
Swijnenburg, R.-J. (Principal investigator)
01/04/2022 → 31/12/2024
Project: Research
Research output
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Impact of resection margin status on recurrence and survival in pancreatic cancer surgery
Tummers, W. S., Groen, J. V., Sibinga Mulder, B. G., Farina-Sarasqueta, A., Morreau, J., Putter, H., van de Velde, C. J., Vahrmeijer, A. L., Bonsing, B. A., Mieog, J. S. & Swijnenburg, R. J., 1 Jul 2019, In: British journal of surgery. 106, 8, p. 1055-1065Research output: Contribution to journal › Article › Academic › peer-review
Open Access170 Citations (Scopus) -
Development and preclinical validation of a cysteine knottin peptide targeting integrin avb6 for near-infrared fluorescent-guided surgery in pancreatic cancer
Tummers, W. S., Kimura, R. H., Abou-Elkacem, L., Beinat, C., Vahrmeijer, A. L., Swijnenburg, R.-J., Willmann, J. K. & Gambhir, S. S., 2018, In: Clinical cancer research. 24, 7, p. 1667-1676Research output: Contribution to journal › Article › Academic › peer-review
38 Citations (Scopus) -
Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts
Swijnenburg, R.-J., Schrepfer, S., Govaert, J. A., Cao, F., Ransohoff, K., Sheikh, A. Y., Haddad, M., Connolly, A. J., Davis, M. M., Robbins, R. C. & Wu, J. C., 2 Sept 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12991-12996 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access266 Citations (Scopus) -
Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma
Tummers, W. S., Farina-Sarasqueta, A., Boonstra, M. C., Prevoo, H. A., Sier, C. F., Mieog, J. S., Morreau, J., van Eijck, C. H., Kuppen, P. J., Bonsing, B. A., Vahrmeijer, A. L. & Swijnenburg, R.-J., 22 Aug 2017, In: Oncotarget. 8, 34, p. 56816-56828 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access35 Citations (Scopus) -
Cluster-randomized crossover trial of chlorhexidine-alcohol versus iodine-alcohol for prevention of surgical-site infection (SKINFECT trial)
Charehbili, A., Koek, M. B. G., de Mol van Otterloo, J. C. A., Bronkhorst, M. W. G. A., van der Zwaal, P., Thomassen, B., Waasdorp, E. J., Govaert, J. A., Bosman, A., van den Bremer, J., Ploeg, A. J., Putter, H., Meijs, A. P., van de Velde, C. J. H., van Gijn, W. & Swijnenburg, R. J., 20 May 2019, In: BJS open. 3, 5, p. 617-622Research output: Contribution to journal › Article › Academic › peer-review
Open Access16 Citations (Scopus)