Personal profile
Specialisation
Vascular Immune Cell Biology
Research interests
Immunology | cardiovascular disease | atherosclerosis | macrophages | epigenetics
My current research integrates fundamental research questions with translational applications and focuses on novel epigenetic regulatory mechanisms of inflammatory responses in macrophages in the context of atherosclerosis.
My previous research experiences include research on immunometabolism related to immune-paralysis in sepsis, molecular mechanisms underlying endothelial activation in systemic lupus erythematosus, and immunometabolism linked to tolerance inducing therapies in transplantation. These projects focus on monocytes, macrophages, myeloid-derived suppressor cells (MDSC) and regulatory T cells (Treg). Furthermore, I have collaborated on systematic (mapping) reviews of animal studies focusing on improving their translational value.
As a passionate, hardworking, and conscientious researcher, I have shown my capacity to combine various activities and commitments. I am an enthusiastic team player keen on learning more about the (dys)function of the human immune system. Additionally, I like to spread my enthusiasm for research and enjoy guiding others through my fields of interest.
Related documents
Education/Academic qualification
Master, MSc Molecular Mechanisms of Disease, Radboudumc
External positions
Student Assistant, Hannover Medical School
BSc Biomedical Sciences, Radboudumc
MSc Molecular Mechanisms of Disease, Radboudumc
Student Assistant, Radboudumc
MSc Fellowship Student, University of Oxford
Student Assistant, Utrecht University
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Research output
-
Regulatory mechanisms of monocytes and macrophages in atherosclerotic cardiovascular disease
Kempkes, R. W. M., 2026, 274 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
-
Human monocyte inflammation in patients with Lp(a) or atherosclerotic cardiovascular disease is not accompanied by changes in chromatin accessibility in circulating classical monocytes
Kempkes, R. W. M., Kraaijenhof, J. M., van Os, B. W., Kaiser, Y., Nurmohamed, N. S., Griffith, G. R., Lutgens, E., Stroes, E. S. G., Prange, K. H. M., de Winther, M. P. J., Kroon, J. & Neele, A. E., 1 Sept 2025, In: Journal of clinical lipidology. 19, 5, p. 1426-1438 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile54 Downloads (Pure) -
Iuis 2023: yEFIS workshop on career development and code-switching
Kempkes, R. W. M., Nikolaou, C., Nabhan, M. & Saidu, N. E. B., Jul 2024, In: European journal of immunology. 54, 7, p. e2451155 2451155.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open AccessFile14 Downloads (Pure) -
Novel insights into the dynamic function of PRC2 in innate immunity
Kempkes, R. W. M., Prinjha, R. K., de Winther, M. P. J. & Neele, A. E., Dec 2024, In: Trends in immunology. 45, 12, p. 1015-1030 16 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile72 Downloads (Pure) -
Equity, equality, and diversity and the young immunologists of Europe: More diverse but still not equal
yEFIS Equity and Diversity working group, 1 Sept 2023, In: European journal of immunology. 53, 9, p. e2350621 2350621.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open AccessFile23 Downloads (Pure)