Research output per year
Research output per year
Personal profile
Research interests
My research focuses on identifying the (integrative) omics signature of depression (using DNA, methylation, gene expression, proteomics) and on finding better treatment for, and identification of, depression subtypes, mainly using data from NESDA (The Netherlands Study of Depression and Anxiety) and NTR (The Netherlands Twin Registry).
I am co PI of PERCIM (Personalized Care for Immuno-Metabolic Depression) (https://psychiatryamsterdam.nl/project/percim/) and was part of the BIOS (Biobank-based integrative omics study) consortium management (https://www.bbmri.nl/acquisition-use-analyze/bios). As NESDA, NTR and BIOS we are part of the large eQTL meta analysis: the eQTLGen Consortium (https://www.eqtlgen.org/).
I am teaching a course on human molecular genetics for the research master 'Genes in Behaviour and Health' (https://vuweb.vu.nl/nl/onderwijs/master/genes-in-behaviour-and-health).
For the publication I (co) authored see my google scholar page: https://scholar.google.nl/citations?user=cHJDM0YAAAAJ&hl=en.
And for the publications from the Consortia I participated in see:
BIOS: https://pubmed.ncbi.nlm.nih.gov/?term=BIOS+Consortium%5BCorporate+Author%5D&sort=date.
eQTLGen: https://pubmed.ncbi.nlm.nih.gov/?sort=date&term=eQTLGen+Consortium%5BCorporate+Author%5D.
See also our conditional eQTL catalog based on NESDA and NTR data:
And the Methylation and RNA-seq QTL catalogs from BIOS:
Email: ri.jansen at amsterdamumc.nl
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Research output
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Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort
Montanari, S., Jansen, R., Schranner, D., Kastenmüller, G., Arnold, M., Janiri, D., Sani, G., Bhattacharyya, S., Mahmoudian Dehkordi, S., Dunlop, B. W., Rush, A. J., Penninx, B. W. H. J., Kaddurah-Daouk, R. & Milaneschi, Y., 1 Dec 2025, In: Translational psychiatry. 15, 1, 65.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Increased ectodysplasin-A2-receptor EDA2R is a ubiquitous hallmark of aging and mediates parainflammatory responses
Barbera, M. C., Guarrera, L., Re Cecconi, A. D., Cassanmagnago, G. A., Vallerga, A., Lunardi, M., Checchi, F., di Rito, L., Romeo, M., Mapelli, S. N., Schoser, B., Generozov, E. V. & Molecular Genetics Group, 1 Dec 2025, In: Nat. Commun.. 16, 1, 1898.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Putting computational models of immunity to the test—An invited challenge to predict B.pertussis vaccination responses
Shinde, P., Willemsen, L., Anderson, M., Aoki, M., Basu, S., Burel, J. G., Cheng, P., Dastidar, S. G., Dunleavy, A., Einav, T., Forschmiedt, J., Fourati, S., Garcia, J., Gibson, W., Greenbaum, J. A., Guan, L., Guan, W., Gygi, J. P., Ha, B. & Hou, J. & 39 others, , 1 Mar 2025, In: PLoS computational biology. 21, 3 March, e1012927.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Running therapy or antidepressants as treatments for immunometabolic depression in patients with depressive and anxiety disorders: A secondary analysis of the MOTAR study
Vreijling, S. R., Penninx, B. W. J. H., Verhoeven, J. E., Teunissen, C. E., Blujdea, E. R., Beekman, A. T. F., Lamers, F. & Jansen, R., 1 Jan 2025, In: Brain, behavior, and immunity. 123, p. 876-883 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 6 Feb 2025, In: Cell. 188, 3, p. 640-652.e9Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus)