Research output per year
Research output per year
Personal profile
Research interests
Renee Schreurs is a postdoctoral fellow in the Autophagy-directed Immunity lab headed by dr. Carla Ribeiro at the Department of Experimental Immunology, Amsterdam UMC (location AMC). She holds a MSc in Neuroscience and completed a PhD on the development of mucosal T cell immunity in the early-life intestine.
Within dr. Ribeiro's lab, Renee's current research focuses on investigating the impact of genetic variation in autophagy pathways on T cell functionality in the context of viral infections such as HIV-1. Additionally, Renee studies the impact of autophagy and extracellular vescicles on intestinal barrier integrity and inflammation using advanced organoid and organoid-immune cell co-culture models through partnerships with the Gutvibrations consortium and Emma Children's Hospital.
Ultimately, the Autophagy-directed Immunity lab aims to harness the therapeutic potential of targeting autophagy mechanisms to intervene with HIV-1, Dengue virus, and SARS-CoV-2 infections.
Specialisation
T cell immunity, intestinal inflammation, mucosal immune system, cell & organoid culture, autophagy, neuroscience, fetal and pediatric immunity, HIV-1
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Collaborations and top research areas from the last five years
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Autophagy-enhancing ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection
Schreurs, R. R. C. E., Koulis, A., Booiman, T., Boeser-Nunnink, B., Cloherty, A. P. M., Rader, A. G., Patel, K. S., Kootstra, N. A. & Ribeiro, C. M. S., 1 Dec 2024, In: Nature communications. 15, 1, 2465.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis
The, S.-M. M. L., Schreurs, R. R. C. E., Drewniak, A., Bakx, R., de Meij, T. G. J., Budding, A. E., Poort, L., Cense, H. A., Heij, H. A., van Heurn, L. W. E., Gorter, R. R. & Bunders, M. J., 2024, In: Frontiers in immunology. 14, p. 1258363 1258363.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
HIV-1 exploits LBPA-dependent intraepithelial trafficking for productive infection of human intestinal mucosa
Rader, A. G., Cloherty, A. P. M., Patel, K. S., Almandawi, D. D. A., Pajkrt, D., Wolthers, K. C., Sridhar, A., van Piggelen, S., Baaij, L. E., Schreurs, R. R. C. E. & Ribeiro, C. M. S., 1 Dec 2024, In: PLoS pathogens. 20, 12, e1012714.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The Neo-Open Reading Frame Peptides That Comprise the Tumor Framome Are a Rich Source of Neoantigens for Cancer Immunotherapy
Martin, M. V., Aguilar-Rosas, S., Franke, K., Pieterse, M., Langelaar, J. V., Schreurs, R., Bijlsma, M. F., Besselink, M. G., Koster, J., Timens, W., Khasraw, M., Ashley, D. M., Keir, S. T., Ottensmeier, C. H., King, E. V., Verheij, J., Waasdorp, C., Valk, P. J. M., Engels, S. A. G. & Oostenbach, E. & 16 others, , 4 Jun 2024, In: Cancer immunology research. 12, 6, p. 759-778 20 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade
Cloherty, A. P. M., Rader, A. G., Patel, K. S., Pérez-Vargas, J., Thompson, C. A. H., Ennis, S., Niikura, M., Wildenberg, M. E., Muncan, V., Schreurs, R. R. C. E., Jean, F. & Ribeiro, C. M. S., 1 Dec 2023, In: Emerging microbes & infections. 12, 1, p. 2195020 2195020.Research output: Contribution to journal › Article › Academic › peer-review
Open Access10 Citations (Scopus)