Personal profile
Research interests
- The role of angiogenic and anti-angiogenic factors in ocular angiogenesis, particularly in AMD and diabetic retinopathy
- The cellular mechanisms underlying loss of the blood-retinal barrier in diabetic retinopathy
- Identification of new genes and mechanisms of angiogenesis
- The role of complement activation and the proteasome in retinal pigment epithelium in the early stages of age-related macular degeneration
- Prospective clinical trials on the use of anti-angiogenic therapy in AMD, diabetic retinopathy and retinal vein occlusions
See also: www.ocular-angiogenesis.nl/
Specialisation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions
Klaassen, I., van Noorden, C. J. F. & Schlingemann, R. O., 2013, In: Progress in retinal and eye research. 34, p. 19-48Research output: Contribution to journal › Article › Academic › peer-review
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VEGF levels in plasma in relation to platelet activation, glycemic control, and microvascular complications in type 1 diabetes
Schlingemann, R. O., van Noorden, C. J. F., Diekman, M. J. M., Tiller, A., Meijers, J. C. M., Koolwijk, P. & Wiersinga, W. M., 2013, In: Diabetes care. 36, 6, p. 1629-1634Research output: Contribution to journal › Article › Academic › peer-review
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CD34 marks angiogenic tip cells in human vascular endothelial cell cultures
Siemerink, M. J., Klaassen, I., Vogels, I. M. C., Griffioen, A. W., van Noorden, C. J. F. & Schlingemann, R. O., 2012, In: Angiogenesis. 15, 1, p. 151-163Research output: Contribution to journal › Article › Academic › peer-review
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The RESTORE Study Ranibizumab Monotherapy or Combined with Laser versus Laser Monotherapy for Diabetic Macular Edema
Mitchell, P., Bandello, F., Schmidt-Erfurth, U., Lang, G. E., Massin, P., Schlingemann, R. O., Sutter, F., Simader, C., Burian, G., Gerstner, O. & Weichselberger, A., 2011, In: Ophthalmology. 118, 4, p. 615-625Research output: Contribution to journal › Article › Academic › peer-review
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Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus
Sohn, E. H., van Dijk, H. W., Jiao, C., Kok, P. H. B., Jeong, W., Demirkaya, N., Garmager, A., Wit, F., Kucukevcilioglu, M., van Velthoven, M. E. J., DeVries, J. H., Mullins, R. F., Kuehn, M. H., Schlingemann, R. O., Sonka, M., Verbraak, F. D. & Abràmoff, M. D., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 19, p. E2655-E2664Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile43 Downloads (Pure)
Courses
Impacts
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Een sterke schakel: Evaluatie ZonMw-programma Goed Gebruik Geneesmiddelen
Schlingemann, R. O. (Participant)
Impact: Economic impacts