Personal profile
Specialisation
Neurosurgery
Research interests
During my PhD, I studied basal ganglia development in a mouse model of Parkinson's disease. During my neurosurgical training, I specialised in deep brain stimulation (DBS) of the basal ganglia. My research interests focus on improving the outcome of DBS surgery in established indications, such as Parkinson's disease and essential tremor, and the application of experimental DBS in new indications, such as psychiatric diseases and disorders of consciousness. Since 2009, I act(ed) as a co-investigator on clinical trials studying subthalamic nucleus versus globus pallidus DBS in Parkinson's disease, nucleus accumbens DBS in obsessive-compulsive disorder, internal capsule and medial forebrain bundle DBS in depression, internal capsule DBS in anorexia nervosa, and general anesthesia versus local anesthesie in DBS for Parkinson's disease. I initiated several research projects to improve the radiological and neurophysiological targeting of DBS surgery. Since 2017, I act as principal investigator of the RECONNECT trial, studying the effects of DBS of the central thalamus in patients with disorders of consciousness, fopr which I created a multidisciplinary national research alliance.
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Awakening after a sleeping pill: Restoring functional brain networks after severe brain injury
Arnts, H., van Erp, W. S., Boon, L. I., Bosman, C. A., Admiraal, M. M., Schrantee, A., Pennartz, C. M. A., Schuurman, R., Stam, C. J., van Rootselaar, A.-F., Hillebrand, A. & van den Munckhof, P., 1 Nov 2020, In: Cortex; a journal devoted to the study of the nervous system and behavior. 132, p. 135-146 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Deep brain stimulation for Parkinson's disease: defining the optimal location within the subthalamic nucleus
Bot, M., Schuurman, P. R., Odekerken, V. J. J., Verhagen, R., Contarino, F. M., de Bie, R. M. A. & van den Munckhof, P., 2018, In: Journal of neurology, neurosurgery, and psychiatry. 89, p. 493-498Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure) -
The Dilemma of Hydrocephalus in Prolonged Disorders of Consciousness
Arnts, H., van Erp, W. S., Sanz, L. R. D., Lavrijsen, J. C. M., Schuurman, R., Laureys, S., Vandertop, W. P. & van den Munckhof, P., 15 Oct 2020, In: Journal of neurotrauma. 37, 20, p. 2150-2156 7 p.Research output: Contribution to journal › Review article › Academic › peer-review
-
Active stimulation site of nucleus accumbens deep brain stimulation in obsessive-compulsive disorder is localized in the ventral internal capsule
van den Munckhof, P., Bosch, D. A., Mantione, M. H. M., Figee, M., Denys, D. A. J. P. & Schuurman, P. R., 2013, In: Acta neurochirurgica. 117, Suppl., p. 53-59Research output: Contribution to journal › Article › Academic › peer-review
-
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons
van den Munckhof, P., Luk, K. C., Ste-Marie, L., Montgomery, J., Blanchet, P. J., Sadikot, A. F. & Drouin, J., 2003, In: Development (Cambridge, England). 130, 11, p. 2535-2542Research output: Contribution to journal › Article › Academic › peer-review
Press/Media
-
TV program Dutch Natonal television on the application of deep brain stimulation in therapy-resistent depression
05/09/2024
1 Media contribution
Press/Media: Press / Media
-
Radio program Dutch National radio on the application of deep brain stimulation in severe psychiatric diseases
13/04/2024
1 Media contribution
Press/Media: Press / Media
-
TV program Dutch National television on the paradoxical awakening of a akinetic mutistic patient following the use of a sleeping pill
02/10/2020
1 Media contribution
Press/Media: Press / Media