Projects per year
Personal profile
Research interests
The current research is related to the oncological aspects of upper GI cancer with the main interest in pancreatic and oesophageal cancer. For pancreatic cancer a nationwide organisation is being installed to organise a trial on the effects of neoadjuvant treatment with chemoradiation prior to operation.
In the benign GI surgery current research is on chronic pancreatitis, bile duct injury and achalasia
Specialisation
Gastro-Intestinal Surgery
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Collaborations and top research areas from the last five years
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Projects
- 2 Active
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DIPLOMA-2x2 Intuitive: Robotic versus open pancreatoduodenectomy in patients with primary resectable cancer in the pancreatic head (DIPLOMA-2x2): a “roll-over” international patient and pathologist-blinded randomized con...
Besselink, M. (Principal investigator) & Busch, O. (Project Leader)
Intuitive Surgical Operations, Inc.
01/01/2024 → 31/12/2028
Project: Research
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Besselink M.G.H.: Pancreatic surgery & Minimally invasive HPB surgery
Besselink, M. (Principal investigator), Busch, O. (Staff), van Hooft, J. (Staff), van Laarhoven, H. (Staff), van Lienden, K. P. (Staff), Agnass, P. (Staff), van Dijk, S. (Staff), van der Geest, L. (Staff), Zwart, M. (Internal PhD candidate), Vogel, J. (Internal PhD candidate), Strijker, M. (Internal PhD candidate), Steen, M. (Internal PhD candidate), Scholten, L. (Internal PhD candidate) & van Rijssen, B. (Internal PhD candidate)
23/03/2015 → …
Project: Research
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Biliary drainage prior to pancreatoduodenectomy with endoscopic ultrasound-guided choledochoduodenostomy versus conventional ERCP: Propensity score-matched study and surgeon survey
Fritzsche, J. A., de Jong, M. J. P., Bonsing, B. A., Busch, O. R., Daams, F., Derksen, W. J. M., van Driel, L. M. J. W., Festen, S., van Geenen, E.-J. M., Hoogwater, F. J. H., Inderson, A., Kuiken, S. D., Liem, M. S. L., Lips, D. J., Nijkamp, M. W., van Santvoort, H. C., Siersema, P. D., Stommel, M. W. J., Venneman, N. G. & Verdonk, R. C. & 12 others, , 2025, (E-pub ahead of print) In: Endoscopy.Research output: Contribution to journal › Article › Academic › peer-review
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Blood Sample Collection in Randomized Controlled Trials for Biomarker Discovery and Validation: Experience of the PREOPANC-2 Trial
Dekker, E. N., Janssen, Q. P., van Dam, J. L., Strijk, G. J., Verkolf, E. M. M., Kandala, S., Dumas, J., Fellah, A., O’Reilly, E. M., Besselink, M. G., van Eijck, C. H. J., Homs, M. Y. V., van Tienhoven, G.-J., Wilmink, J. W., Mustafa, D. A. M., Groot Koerkamp, B. & Dutch Pancreatic Cancer Group, Jul 2025, In: Annals of surgical oncology. 32, 7, p. 5092-5101 10 p., 102019.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Computer-Aided Decision Support and 3D Models in Pancreatic Cancer Surgery: A Pilot Study
Rasenberg, D. W. M., Ramaekers, M., Jacobs, I., Pluyter, J. R., Geurts, L. J. F., Yu, B., van der Ven, J. C. P., Nederend, J., de Hingh, I. H. J. T., Bonsing, B. A., Vahrmeijer, A. L., van der Harst, E., den Dulk, M., van Dam, R. M., Groot Koerkamp, B., Erdmann, J. I., Daams, F., Busch, O. R., Besselink, M. G. & te Riele, W. W. & 5 others, , 1 Mar 2025, In: Clinical Chemistry. 14, 5, 1567.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Cost-analysis of implementing robot-assisted versus open pancreatoduodenectomy
HPB-Amsterdam, 2025, (Accepted/In press) In: Annals of surgery. 10.1097/SLA.0000000000006665.Research output: Contribution to journal › Article › Academic › peer-review
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Impact of patient age on outcome of minimally invasive versus open pancreatoduodenectomy: a propensity score matched study
Emmen, A. M. L. H., Jones, L. R., Wei, K., Busch, O., Shen, B., Fusai, G. K., Shyr, Y.-M., Khatkov, I., White, S., Boggi, U., Kerem, M., Molenaar, I. Q., Koerkamp, B. G., Saint-Marc, O., Dokmak, S., van Dieren, S., Rozzini, R., Festen, S., Liu, R. & Jang, J.-Y. & 2 others, , Jan 2025, In: HPB. 27, 1, p. 102-110 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile
Datasets
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Association of the location of pancreatic ductal adenocarcinoma (head, body, tail) with tumor stage, treatment, and survival: a population-based analysis
Besselink, M. G. (Creator), van Erning, F. N. (Contributor), Mackay, T. M. (Creator), van der Geest, L. G. M. (Contributor), Groot, K. B. (Contributor), van Laarhoven, H. W. M. (Contributor), Bonsing, B. A. (Creator), Wilmink, J. W. (Creator), van Santvoort, H. C. (Contributor), de Vos-Geelen, J. (Contributor), van Eijck, C. H. J. (Contributor), Busch, O. R. (Creator) & Lemmens, V. E. (Creator), Taylor & Francis, 2018
DOI: 10.6084/m9.figshare.7146152.v1, https://tandf.figshare.com/articles/Association_of_the_location_of_pancreatic_ductal_adenocarcinoma_head_body_tail_with_tumor_stage_treatment_and_survival_a_population-based_analysis/7146152/1
Dataset
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Readily available biomarkers predict poor survival in metastatic pancreatic cancer
Strijker, M. (Creator), van Veldhuisen, E. (Contributor), van der Geest, L. G. (Contributor), Busch, O. R. (Creator), Bijlsma, M. F. (Creator), Haj Mohammad, N. (Contributor), Homs, M. Y. (Creator), van Hooft, J. E. (Contributor), Verheij, J. (Creator), de Vos-Geelen, J. (Contributor), Wilmink, J. W. (Creator), Steyerberg, W. E. W. (Creator), Besselink, M. G. (Creator) & van Laarhoven, H. W. (Contributor), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14169623.v1, https://tandf.figshare.com/articles/dataset/Readily_available_biomarkers_predict_poor_survival_in_metastatic_pancreatic_cancer/14169623/1
Dataset
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Readily available biomarkers predict poor survival in metastatic pancreatic cancer
Strijker, M. (Creator), van Veldhuisen, E. (Contributor), van der Geest, L. G. (Contributor), Busch, O. R. (Creator), Bijlsma, M. F. (Creator), Haj Mohammad, N. (Contributor), Homs, M. Y. (Creator), van Hooft, J. E. (Contributor), Verheij, J. (Creator), de Vos-Geelen, J. (Contributor), Wilmink, J. W. (Creator), Steyerberg, W. E. W. (Contributor), Besselink, M. G. (Creator) & van Laarhoven, H. W. (Contributor), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14169623, https://tandf.figshare.com/articles/dataset/Readily_available_biomarkers_predict_poor_survival_in_metastatic_pancreatic_cancer/14169623
Dataset
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Readily available biomarkers predict poor survival in metastatic pancreatic cancer
Strijker, M. (Creator), van Veldhuisen, E. (Contributor), van der Geest, L. G. (Contributor), Busch, O. R. (Creator), Bijlsma, M. F. (Creator), Haj Mohammad, N. (Contributor), Homs, M. Y. (Creator), van Hooft, J. E. (Contributor), Verheij, J. (Creator), de Vos-Geelen, J. (Contributor), Wilmink, J. W. (Creator), Steyerberg, W. E. W. (Contributor), Besselink, M. G. (Creator) & van Laarhoven, H. W. (Contributor), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14169623.v2, https://tandf.figshare.com/articles/dataset/Readily_available_biomarkers_predict_poor_survival_in_metastatic_pancreatic_cancer/14169623/2
Dataset