Research output per year
Research output per year
Personal profile
Research interests
Nicolien C. de Clercq is medical oncologist and painspecialist at Amsterdam University Medical Centers, with academic affiliations to the University of Amsterdam and the Vrije Universiteit Amsterdam. She obtained her PhD on the role of the gut microbiome in cancer and host metabolism
De Clercq is the first physician in the Netherlands formally trained as both an medical oncologist and a pain medicine specialist. Her research focuses on supportive care in oncology and oncological pain, with particular attention to complex cancer pain, opioid-related toxicity, palliative care, and gut microbiota–immunity interactions. Her work bridges translational research and clinical practice, aiming to improve quality of life and treatment outcomes for patients with cancer through integrated, person-centered care.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Research output
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Targeting the gut microbiota as a treatment for obesity and cancer cachexia
Giannakogeorgou, A., van den Ende, T., Verhaar, B. J. H., de Clercq, N., van Laarhoven, H. W. M. & Nieuwdorp, M., Dec 2025, In: Expert opinion on emerging drugs. 30, 4, p. 225-240 16 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Fecal, duodenal, and tumor microbiota composition of esophageal carcinoma patients, a longitudinal prospective cohort
van den Ende, T., de Clercq, N. C., Davids, M., Goedegebuure, R., Doeve, B. H., Ebrahimi, G., Buijsen, J., Hoekstra, R., Mohammad, N. H., Bijlsma, M. F., Nieuwdorp, M. & van Laarhoven, H. W. M., 1 Nov 2024, In: Journal of the National Cancer Institute. 116, 11, p. 1834-1844 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile32 Downloads (Pure) -
Novel Proteome Targets Marking Insulin Resistance in Metabolic Syndrome
Warmbrunn, M. V., Bahrar, H., de Clercq, N. C., Koopen, A. M., de Groot, P. F., Rutten, J., Joosten, L. A. B., Kootte, R. S., Bouter, K. E. C., ter Horst, K. W., Hartstra, A. V., Serlie, M. J., Soeters, M. R., van Raalte, D. H., Davids, M., Levin, E., Herrema, H., Riksen, N. P., Netea, M. G. & Groen, A. K. & 1 others, , 10 Jun 2024, In: Nutrients. 16, 12Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile35 Downloads (Pure) -
Fecal microbiota transplantation from overweight or obese donors in cachectic patients with advanced gastroesophageal cancer: A randomized, double-blind, placebo-controlled, Phase II Study
de Clercq, N. C., van den Ende, T., Prodan, A., Hemke, R., Davids, M., Pedersen, H. K., Nielsen, H. B., Groen, A. K., de Vos, W. M., van Laarhoven, H. W. M. & Nieuwdorp, M., 1 Jul 2021, In: Clinical cancer research. 27, 13, p. 3784-3792 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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Metabolite profile of treatment-naive metabolic syndrome subjects in relation to cardiovascular disease risk
Warmbrunn, M. V., Koopen, A. M., de Clercq, N. C., de Groot, P. F., Kootte, R. S., Bouter, K. E. C., ter Horst, K. W., Hartstra, A. V., Serlie, M. J., Ackermans, M. T., Soeters, M. R., van Raalte, D. H., Davids, M., Nieuwdorp, M. & Groen, A. K., 1 Apr 2021, In: Metabolites. 11, 4, 236.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile27 Downloads (Pure)