Projects per year
Personal profile
Specialisation
venous thromboembolism, deep vein thrombosis, pulmonary embolism, epidemiology, anticoagulation
Research interests
My research mainly focuses on the epidemiology, diagnosis, prediction, and treatment of venous thromboembolism, in particular in patients with cancer. We have an interest in developing risk assessment tools to cancer patients at high risk of venous thromboembolism, by using both clinical data and genetic information from tumor biopsies.
I am also interested in cardiovascular complications in cancer patients, in particular as a result of immune checkpoint inhibition. We study the effects of immune checkpoint inhibition on atherosclerosis and hypercoagulability in clinical studies.
Finally, I am involved in clinical studies evaluating the efficacy and safety of factor XI inhibitors, a novel class of anticoagulants that may be associated with a lower risk of bleeding than tradiational anticoagulation.
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Collaborations and top research areas from the last five years
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Veni ES, van: Veni 2023 / Veni 2023 Grant Decision - File number 09150162310132
van Es, N. (Principal investigator)
01/01/2025 → 01/01/2028
Project: Research
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ISTH NETWORKING EVENT 2024: ISTH NETWORKING EVENT 2024
van Es, N. (Principal investigator)
31/05/2024 → 31/10/2025
Project: Research
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Additional analyses Hokusai VTE Cancer: Additional analyses Hokusai VTE Cancer
van Es, N. (Principal investigator)
01/08/2022 → 30/07/2026
Project: Research
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ICATHA project: ICATHA project
van Es, N. (Principal investigator)
01/06/2022 → 31/12/2027
Project: Research
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PREVENT ES: PREdicting VENous Thromboembolism in pancreatic cancer patients (PREVENT)
van Es, N. (Principal investigator)
01/05/2022 → 04/05/2025
Project: Research
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Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism
Raskob, G. E., van Es, N., Verhamme, P., Carrier, M., Di Nisio, M., Garcia, D., Grosso, M. A., Kakkar, A. K., Kovacs, M. J., Mercuri, M. F., Meyer, G., Segers, A., Shi, M., Wang, T.-F., Yeo, E., Zhang, G., Zwicker, J. I., Weitz, J. I., Büller, H. R. & AUTHOR GROUP, 2018, In: New England journal of medicine. 378, 7, p. 615-624Research output: Contribution to journal › Article › Academic › peer-review
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Ruling out pulmonary embolism across different healthcare settings: A systematic review and individual patient data meta-analysis
Geersing, G.-J., Takada, T., Klok, F. A., Büller, H. R., Courtney, D. M., Freund, Y., Galipienzo, J., le Gal, G., Ghanima, W., Kline, J. A., Huisman, M. V., Moons, K. G. M., Perrier, A., Parpia, S., Robert-Ebadi, H., Righini, M., Roy, P.-M., van Smeden, M., Stals, M. A. M. & Wells, P. S. & 3 others, , 1 Jan 2022, In: PLoS medicine. 19, 1, e1003905.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism A Systematic Review and Meta-analysis of Individual Patient Data
van Es, N., Le Gal, G., Otten, H.-M., Robin, P., Piccioli, A., Lecumberri, R., Jara-Palomares, L., Religa, P., Rieu, V., Rondina, M., Beckers, M. M., Prandoni, P., Salaun, P.-Y., Di Nisio, M., Bossuyt, P. M., Büller, H. R. & Carrier, M., 2017, In: Annals of internal medicine. 167, 6, p. 410-417Research output: Contribution to journal › Review article › Academic › peer-review
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Wells Rule and d-Dimer Testing to Rule Out Pulmonary Embolism: A Systematic Review and Individual-Patient Data Meta-analysis
van Es, N., van der Hulle, T., van Es, J., den Exter, P. L., Douma, R. A., Goekoop, R. J., Mos, I. C. M., Galipienzo, J., Kamphuisen, P. W., Huisman, M. V., Klok, F. A., Büller, H. R. & Bossuyt, P. M., 2016, In: Annals of internal medicine. 165, 4, p. 253-261Research output: Contribution to journal › Review article › Academic › peer-review
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Platelet RNA sequencing for cancer screening in patients with unprovoked venous thromboembolism: a prospective cohort study
Mulder, F. I., Kraaijpoel, N., Carrier, M., Guman, N. A., Jara-Palomares, L., Di Nisio, M., Ageno, W., Beyer-Westendorf, J., Klok, F. A., Vanassche, T., Otten, H.-M. B., Cosmi, B., Wolde, M. T., In 't Veld, S. G. J. G., Post, E., Ramaker, J., Zwaan, K., Peters, M., Delluc, A. & Kamphuisen, P. W. & 7 others, , 1 Apr 2023, In: Journal of thrombosis and haemostasis : JTH. 21, 4, p. 905-916 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access