Projects per year
Personal profile
Research interests
M.E.D. Chamuleau, MD PhD is an internist-hematologist with specific expertise in high-grade B-cell Non-Hodgkin lymphoma.
She is chair of the national HOVON Lymphoma Working Group and chair of the internarional Burkitt Lymphoma Network.
Regarding clinical research: she is the principal investigator of 3 clinical interventional HOVON trials for patients with MYC-driven lymphoma such as double-hit lymphoma and Burkitt lymphoma (HOVON 127, 130 and 152). She is also the principal investigator of 2 non-interventional HOVON studies (HOVON 900 and 902) and supervising population-based research on lymphoma in collaboration with the IKNL (PhD D. Issa).
Regarding pre-clinical research she focuses on improving immuno-chemotherapy in high grade B-cell Non-Hodgkin lymphomas by using hexabodies and duobodies (post-doc H. van der Horst), by MYC modulation (PhD A.V. de Jonge), response monitoring by liquid biopsies (PhD S. Wang), and development of fitter CAR T cells (PhD T. Knol).
Specialisation
Hematology (aggressive B-cel Non-Hodgkin Lymphoma)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Projects
- 1 Active
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MCCF Spatial Biology Grant; Map the stromal cell landscape in DLBCL-NOS and HGBL-MYC
de Winde, L. (Principal investigator), Chamuleau, M. (Project Member) & de Jonge, V. (Project Member)
01/09/2025 → 31/07/2026
Project: Research
Research output
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Diffuse large B-cell lymphoma with MYC gene rearrangements: Current perspective on treatment of diffuse large B-cell lymphoma with MYC gene rearrangements; case series and review of the literature
de Jonge, A. V., Roosma, T. J. A., Houtenbos, I., Vasmel, W. L. E., van de Hem, K., de Boer, J. P., van Maanen, T., Lindauer-van der Werf, G., Beeker, A., Timmers, G. J., Schaar, C. G., Soesan, M., Poddighe, P. J., de Jong, D. & Chamuleau, M. E. D., Mar 2016, In: European Journal of Cancer. 55, p. 140-146 7 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Treatment of sporadic Burkitt lymphoma in adults, a retrospective comparison of four treatment regimens
Oosten, L. E. M., Chamuleau, M. E. D., Thielen, F. W., de Wreede, L. C., Siemes, C., Doorduijn, J. K., Smeekes, O. S., Kersten, M. J., Hardi, L., Baars, J. W., Demandt, A. M. P., Stevens, W. B. C., Nijland, M., van Imhoff, G. W., Brouwer, R., Uyl-de Groot, C. A., Kluin, P. M., de Jong, D. & Veelken, H., 1 Feb 2018, In: Annals of hematology. 97, 2, p. 255-266 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
Successful Treatment of MYC rearrangement Positive Large B Cell Lymphoma Patients with R-CHOP21 Plus Lenalidomide: Results of a Multicenter Phase II HOVON Trial
Chamuleau, M. E. D., Nijland, M., Zijlstra, J. M., Mous, R., Lugtenburg, P. J., Dierickx, D., Imhoff, G. V., Vermaat, J., Bakunina, K., Marijt, E. W. A., Visser, O., Mandigers, C., Bilgin, Y., Burggraaff, C., Hoekstra, O., Jong, D. D. & Kersten, M. J., 21 Nov 2018, In: Blood. 132, Suppl 1, p. 786 1 p.Research output: Contribution to journal › Meeting Abstract › Academic
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Treatment and relative survival in very elderly patients with DLBCL in The Netherlands: a population-based study, 1989 to 2015
Dinmohamed, A. G., Issa, D. E., van der Poel, M. W. M., Schouten, H. C., Lugtenburg, P. J., Chamuleau, M. E. D., Zweegman, S. & Visser, O., 2017, In: Blood. 1, 21, p. 1839-1841 3 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open AccessFile -
CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering
Oostindie, S. C., van der Horst, H. J., Lindorfer, M. A., Cook, E. M., Tupitza, J. C., Zent, C. S., Burack, R., VanDerMeid, K. R., Strumane, K., Chamuleau, M. E. D., Mutis, T., de Jong, R. N., Schuurman, J., Breij, E. C. W., Beurskens, F. J., Parren, P. W. H. I. & Taylor, R. P., 31 Aug 2019, In: Haematologica. 104, 9, p. 1841-1852 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Downloads (Pure)
Activities
- 1 Membership of board
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HOVON Data Centre, Rotterdam, Netherlands (External organisation)
Chamuleau, M. (Member)
1 May 2010 → 1 May 2022Activity: Membership › Membership of board › Academic