Cerebral glucose metabolism, perioperative neurocognitive disorders, circadian rhythm

My research interests are centered around three primary pillars: cerebral glucose metabolism, circadian rhythm, and perioperative neurocognitive disorders (PNCD).

My research on cerebral glucose metabolism focuses on changes in glucose transport and alternative glycolysis processes (particularly in the perioperative period and following subarachnoid hemorrhage or traumatic brain injury), and the effects of elevated cerebrospinal fluid glucose levels on the neurotoxic polyol pathway.

In addition, I investigate the effects of surgery and anesthesia on the sleep-wake cycle of children and adults, examining the physiological and metabolic effects on postoperative recovery. Furthermore, I study the sleep quality of children and adults in various hospital departments.

My research on perioperative neurocognitive disorders aims to enhance prediction and diagnosis methods for PNCD in older adults undergoing surgery. This includes the prospective comparison of detection methods for perioperative neurocognitive disorders and the exploration of perioperative brain functioning, including the influence of intraoperative hypotension and anesthesia on cognition.