Projects per year
Personal profile
Specialisation
Immunotherapy, cancer, inflammatory diseases, antibodies, immunology
Research interests
Since the start of her career Prof. dr. van Egmond has studied the function of antibodies, with emphasis on understanding the role of immunoglobulin A (IgA) in physiology and pathology. Her research also addresses (1) the contribution of abnormal antibody responses in chronic inflammation and autoimmunity and (2) monoclonal antibody therapy of cancer. Prof. dr. van Egmond’s research is highly translational and she has a cross appointment with the Department of Surgery and the Department of Molecular Cell Biology and Immunology at Amsterdam UMC, to facilitate the rapid progression of pre-clinical findings into clinical applications. Prof.dr. van Egmond is the spokeswoman of the Dutch Society for Immunology, and since the COVID-19 crisis she has an active role in providing information on the immune system and vaccines to the general public.
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Collaborations and top research areas from the last five years
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Immunoglobulin A Antibodies as Biomarker for Multiple Sclerosis Progression
van Egmond, M. (Principal investigator)
15/09/2020 → …
Project: Research
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Immunoglobulin A Antibodies as Biomarker for Multiple Sclerosis Progression
van Egmond, M. (Principal investigator)
Congressionally Directed Medical Research Programs
01/01/2019 → …
Project: Research
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From IgA to IgG, the road to effective anti-cancer treatment: How to overcome the immunosuppressive environment that hampers monoclonal antibody therapy of cancer?
van Egmond, M. (Principal investigator)
01/09/2015 → 31/08/2018
Project: Research
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An act of revision: IgA in health and disease
van Gool, M. M. J., 26 Jan 2023, s.l.: Ridderprint. 225 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
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Surgery for colorectal cancer: a trigger for liver metastases development? New insights into the underlying mechanisms
Grewal, S. K., 27 Oct 2022, 218 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
Open Access -
Targeting myeloid cells with bispecific antibodies as novel immunotherapies of cancer
Sewnath, C., Behrens, L. & van Egmond, M., 19 Jul 2022, In: Expert opinion on biological therapy. 22, 8, p. 983–995 13 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access10 Citations (Scopus) -
Intrathecal IgG and IgM synthesis correlates with neurodegeneration markers and corresponds to meningeal B cell presence in MS
Rodriguez-Mogeda, C., van Gool, M. M. J., van der Mast, R., Nijland, R., Keasberry, Z., van de Bovekamp, L., van Delft, M. A. M., Picon, C., Reynolds, R., Killestein, J., Teunissen, C. E., de Vries, H. E., van Egmond, M. & Witte, M. E., 1 Dec 2024, In: Scientific reports. 14, 1, 25540.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Antagonizing FcαR1 (CD89) as treatment in IgA-mediated chronic inflammation and autoimmunity
van Delft, M. A. M., Aleyd, E., Mast, R. V. D., de Jong, N., Boon, L., Simons, P. J. & van Egmond, M., 2023, In: Frontiers in immunology. 14, p. 1118539 1118539.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)
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Dutch Cancer Foundation (External organisation)
van Egmond, M. (Member)
1 Jan 2024 → …Activity: Membership › Membership of board › Academic
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Neutrophils and cancer immunotherapy
van Egmond, M. (Speaker)
22 Nov 2023Activity: Talk or presentation › Invited talk › Academic
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Novel FcαRI Bispecific Antibody Immunocytokines for the Recruitment of Myeloid Effector Cells in Cancer Therapy
van Egmond, M. (Speaker)
14 Nov 2023Activity: Talk or presentation › Invited talk › Academic
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Novel Bispecific Antibody Immunocytokines for the Recruitment of Myeloid Effector Cells in Cancer Therapy
van Egmond, M. (Speaker)
21 Jun 2023Activity: Talk or presentation › Invited talk › Academic
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Academic founder and consultant
van Egmond, M. (Consultant)
1 Jun 2023 → …Activity: Consultancy › Academic
Prizes
Press/Media
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TV interview Tijd voor Max over immuuntherapie van kanker
02/11/2023
1 Media contribution
Press/Media: Press / Media
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Interview tijdschrift ‘Kijk over immuuntherapie van kanker
01/11/2023
1 Media contribution
Press/Media: Press / Media
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