Research output per year
Research output per year
Personal profile
Research interests
- Cancer stem cells
- Colorectal cancer
- Cancer subtypes
- Tumor evolution
Specialisation
Cancer research
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Vice President, Head of Discovery Oncology, Genentech Inc.
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
de Sousa E Melo, F., Wang, X., Jansen, M., Fessler, E., Trinh, A., de Rooij, L. P. M. H., de Jong, J. H., de Boer, O. J., van Leersum, R., Bijlsma, M. F., Rodermond, H., van der Heijden, M., van Noesel, C. J. M., Tuynman, J. B., Dekker, E., Markowetz, F., Medema, J. P. & Vermeulen, L., 2013, In: Nature medicine. 19, 5, p. 614-618Research output: Contribution to journal › Article › Academic › peer-review
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The consensus molecular subtypes of colorectal cancer
Guinney, J., Dienstmann, R., Wang, X., de Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., Bot, B. M., Morris, J. S., Simon, I. M., Gerster, S., Fessler, E., de Sousa E Melo, F., Missiaglia, E., Ramay, H., Barras, D. & Homicsko, K. & 20 others, , 2015, In: Nature medicine. 21, 11, p. 1350-1356Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation
Vermeulen, L., Morrissey, E., van der Heijden, M., Nicholson, A. M., Sottoriva, A., Buczacki, S., Kemp, R., Tavaré, S. & Winton, D. J., 2013, In: Science. 342, 6161, p. 995-998Research output: Contribution to journal › Article › Academic › peer-review
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Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
Medema, J. P. & Vermeulen, L., 2011, In: Nature. 474, 7351, p. 318-326Research output: Contribution to journal › Review article › Academic › peer-review
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From tumour heterogeneity to advances in precision treatment of colorectal cancer
Punt, C. J. A., Koopman, M. & Vermeulen, L., 2017, In: Nature reviews. Clinical oncology. 14, 4, p. 235-246Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile1 Downloads (Pure)
Datasets
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Additional file 8 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626329.v1, https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626329/1
Dataset
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Additional file 9 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626332, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626332
Dataset
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Additional file 8 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626329, https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626329
Dataset
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Additional file 2 of Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development
Adam, R. S. (Creator), van Neerven, S. M. (Contributor), Pleguezuelos-Manzano, C. (Creator), Simmini, S. (Creator), Léveillé, N. (Creator), de Groot, N. E. (Contributor), Holding, A. N. (Creator), Markowetz, F. (Creator) & Vermeulen, L. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.13331696, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Intestinal_region-specific_Wnt_signalling_profiles_reveal_interrelation_between_cell_identity_and_oncogenic_pathway_activity_in_cancer_development/13331696
Dataset
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Additional file 9 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626332.v1, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626332/1
Dataset