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Collaborations and top research areas from the last five years
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Clonal dispersal is associated with tumor heterogeneity and poor prognosis in colorectal cancer
Baglamis, S., Sheraton, V. M., van Neerven, S. M., Logiantara, A., Nijman, L. E., Hageman, L. A., Léveillé, N., Elbers, C. C., Bijlsma, M. F., Vermeulen, L., Krawczyk, P. M. & Lenos, K. J., 16 May 2025, In: iScience. 28, 5, 112403.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Downloads (Pure) -
Colorectal cancer peritoneal metastasis is promoted by tissue-specific fibroblasts that can arise in response to various local disorders
Ramos, C., Walterskirchen, N., Knöbl, V., Zotter, C., Müller, C., Gerakopoulos, V., Rauch, A., Falk, L., Sachet, M., D'Angelo, E., Agostini, M., Pils, D., Aust, S., Grusch, M., Herzog, R., Kratochwill, K., le Blanc, S., Lenos, K. J., Vermeulen, L. & Riss, S. & 7 others, , 28 Nov 2025, In: Cancer letters. 633, 217686.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure) -
Identifying colorectal cancer-specific vulnerabilities in the Wnt-driven long non-coding transcriptome
Schwarzmueller, L. J., Adam, R. S., Moreno, L. F., Nijman, L. E., Logiantara, A., Eleonora, S., Bril, O., Vromans, S., De Groot, N. E., Giugliano, F. P., Stepanova, E., Muncan, V., Elbers, C. C., Lenos, K. J., Zwijnenburg, D. A., Van Eijndhoven, M. A. J., Pegtel, D. M., Van Neerven, S. M., Loayza-Puch, F. & Dadali, T. & 5 others, , 1 Apr 2025, In: Gut. 74, 4, p. 571-585 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Peritoneal resident macrophages constitute an immunosuppressive environment in peritoneal metastasized colorectal cancer
Saris, J., Li Yim, A. Y. F., Bootsma, S., Lenos, K. J., Franco Fernandez, R., Khan, H. N., Verhoeff, J., Poel, D., Mrzlikar, N. M., Xiong, L., Schijven, M. P., van Grieken, N. C. T., Kranenburg, O., Wildenberg, M. E., Logiantara, A., Jongerius, C., Garcia Vallejo, J. J., Gisbertz, S. S., Derks, S. & Tuynman, J. B. & 3 others, , 1 Dec 2025, In: Nat. Commun.. 16, 1, 3669.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Downloads (Pure) -
Spatial Heterogeneity, Stromal Phenotypes, and Therapeutic Vulnerabilities in Colorectal Cancer Peritoneal Metastasis
Ong, C.-A. J., Zhao, J. J., Liu, Y., Srivastava, S., Chia, D. K. A., Quek, Y. E., Fan, X., Ma, H., Huang, K. K., Sheng, T., Tan, Q. X., Ng, G., Tan, J. W. S., Lee, J.-Y. J., Loo, L.-H., Chong, L. Y., Ong, X. W., Tay, S. T., Hagihara, T. & Tan, A. & 27 others, , 15 Jun 2025, In: Clinical cancer research. 31, 12, p. 2515-2529 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile39 Downloads (Pure)
Datasets
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Additional file 9 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626332.v1, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626332/1
Dataset
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Additional file 8 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626329.v1, https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626329/1
Dataset
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Additional file 8 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626329, https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626329
Dataset
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Additional file 9 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626332, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626332
Dataset