Personal profile
Research interests
I investigate the immunological mechanisms driving pathologies of the upper and lower airways, including asthma, allergy, and chronic rhinitis. My research focuses on the role of airway epithelium as a key mediator of inflammation and how interactions between structural cells and immune cells, particularly innate lymphoid cells, shape the local tissue environment that underlies airway disease.
To advance precision medicine, I develop human cell platforms as models for predicting individual patient responses to therapeutics.
Specialisation
Pathologies of the human airways, asthma, allergy, translational research, innate immunity, innate lymphoid cells
Education/Academic qualification
PhD, Immunological mechanisms underlying chronic inflammatory diseases of the upper airways, Universiteit van Amsterdam
1 Jan 2013 → 31 Dec 2016
Award Date: 18 Jan 2017
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response
Golebski, K., Layhadi, J. A., Sahiner, U., Steveling-Klein, E. H., Lenormand, M. M., Li, R. C. Y., Bal, S. M., Heesters, B. A., Vilà-Nadal, G., Hunewald, O., Montamat, G., He, F. Q., Ollert, M., Fedina, O., Lao-Araya, M., Vijverberg, S. J. H., Maitland-van der Zee, A.-H., van Drunen, C. M., Fokkens, W. J. & Durham, S. R. & 2 others, , 9 Feb 2021, In: Immunity. 54, 2, p. 291-307.e7Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation
Golebski, K., Ros, X. R., Nagasawa, M., van Tol, S., Heesters, B. A., Aglmous, H., Kradolfer, C. M. A., Shikhagaie, M. M., Seys, S., Hellings, P. W., van Drunen, C. M., Fokkens, W. J., Spits, H. & Bal, S. M., 2019, In: Nature communications. 10, 1, 2162.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile16 Downloads (Pure) -
Plasticity of innate lymphoid cell subsets
Bal, S. M., Golebski, K. & Spits, H., 1 Sept 2020, In: Nature reviews. Immunology. 20, 9, p. 552-565 14 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile38 Downloads (Pure) -
The multi-faceted role of allergen exposure to the local airway mucosa
Golebski, K., Röschmann, K. I. L., Toppila-Salmi, S., Hammad, H., Lambrecht, B. N., Renkonen, R., Fokkens, W. J. & van Drunen, C. M., 2013, In: Allergy. 68, 2, p. 152-160Research output: Contribution to journal › Review article › Academic › peer-review
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Toward precision medicine: Inflammatory nasal epithelial transcriptomic profiles in long COVID
Baalbaki, N., Blankestijn, J. M., Kazer, S. W., Abdel-Aziz, M. I., Bloemsma, L. D., Bogaard, H. J., Cornelissen, M. E. B., van Drunen, C. M., van Egmond, D., Nossent, E. J., Walsh, J. M. L. & P4O2 consortium, Sept 2025, In: Journal of allergy and clinical immunology. 156, 3, p. 790-802 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile18 Downloads (Pure)