Personal profile
Research interests
HIV-1 restriction factors/ Innate immunity
Cellular factors essential for post-entry steps in the HIV-1 replication cycle
Cellular host-range of the HIV-1 based lentiviral vector
Development of lentiviral vectors for gene therapy
HBV therapy response markers
Specialisation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation is associated with the subsequent reduction in the viral reservoir
van Paassen, P. M., Pasternak, A. O., Bolluyt, D. C., van Dort, K. A., van Nuenen, A. C., Maurer, I., Boeser-Nunnink, B., Buchholtz, N. V. E. J., Mahmoudi, T., Lungu, C., van Crevel, R., Rokx, C., Symons, J., Nijhuis, M., van der Veen, A. L. I. P., Vogt, L., Klouwens, M. J., Prins, J. M., Kootstra, N. A. & de Bree, G. J., 23 Jan 2026, In: eLife. 14Research output: Contribution to journal › Article › Academic › peer-review
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Treatment in acute HIV infection only temporarily preserves monocyte function: a comparative cohort study in adult males
Vlaming, K. E., van Paassen, P. M., van Hamme, J. L., Schonherr, S., Kaptein, T. M., van Dort, K., Maurer, I., van Crevel, R., Rokx, C., Vogt, L. & NOVA Study Team, Dec 2025, In: EBioMedicine. 122, 105997.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Downloads (Pure) -
A Robust Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Specific T- and B-Cell Response Is Associated With Early Viral Clearance in SARS-CoV-2 Omicron-Infected Immunocompromised Individuals
Vergouwe, M., Biemond, J. J., van der Straten, K., van Pul, L., Kerster, G., Claireaux, M., Burger, J. A., van Dort, K. A., Kootstra, N. A., Jonges, M., Welkers, M. R. A., TURN-COVID study group, Bomers, M. K. & van Ittersum, F. J., 15 Oct 2024, In: The Journal of infectious diseases. 230, 4, p. e860-e871Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile32 Downloads (Pure) -
Energy demanding RNA and protein metabolism drive dysfunctionality of HIV-specific T cell changes during chronic HIV infection
van Pul, L., Stunnenberg, M., Kroeze, S., van Dort, K. A., Boeser-Nunnink, B. D. M., Harskamp, A. M., Geijtenbeek, T. B. H. & Kootstra, N. A., 1 Oct 2024, In: PLoS ONE. 19, 10 October, e0298472.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Human Immunodeficiency Virus–Induced Interferon-Stimulated Gene Expression Is Associated With Monocyte Activation and Predicts Viral Load: Open Forum Infectious Diseases
van Pul, L., van Dort, K. A., Girigorie, A. F., Maurer, I., Harskamp, A. M. & Kootstra, N. A., 2024, In: Open Forum Infect. Dis.. 11, 8Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile27 Downloads (Pure)