Personal profile
Research interests
Reciprocal interactions between coagulation and inflammation in the context of kidney diseases.
Current research programmes:
- The fibrinolytic system in renal disease
- Active Protein C (APC) and the endothelial protein C receptor (EPCR) in acute kidney injury and renal allograft rejection
- APC and EPCR in antiphospholipid antibody-induced renal thrombotic microangiopathy
- Platelets and platelet-derived microparticles (PMP) in acute kidney injury and renal allograft rejection
Specialisation
Pathologist
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps
Jansen, M. P. B., Emal, D., Teske, G. J. D., Dessing, M. C., Florquin, S. & Roelofs, J. J. T. H., 2017, In: Kidney international. 91, 2, p. 352-364Research output: Contribution to journal › Article › Academic › peer-review
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Renal endothelial protein C receptor expression and shedding during diabetic nephropathy
Lattenist, L., Ochodnický, P., Ahdi, M., Claessen, N., Leemans, J. C., Satchell, S. C., Florquin, S., Gerdes, V. E. & Roelofs, J. J. T. H., 2016, In: Journal of thrombosis and haemostasis. 14, 6, p. 1171-1182Research output: Contribution to journal › Article › Academic › peer-review
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Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection
Lattenist, L., Kers, J., Claessen, N., ten Berge, I. J. M., Bemelman, F. J., Florquin, S. & Roelofs, J. J. T. H., 2013, In: PLoS ONE. 8, 5, p. e64994Research output: Contribution to journal › Article › Academic › peer-review
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Activated protein C protects against renal ischaemia/reperfusion injury, independent of its anticoagulant properties
Lattenist, L., Jansen, M. P. B., Teske, G., Claessen, N., Meijers, J. C. M., Rezaie, A. R., Esmon, C. T., Florquin, S. & Roelofs, J. J. T. H., 2016, In: Thrombosis and haemostasis. 116, 1, p. 124-133Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Downloads (Pure) -
Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction
Jansen, M. P. B., Pulskens, W. P., Butter, L. M., Florquin, S., Juffermans, N. P., Roelofs, J. J. T. H. & Leemans, J. C., 2018, In: Shock (Augusta, Ga.). 49, 3, p. 301-310Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile18 Downloads (Pure)