Research output per year
Research output per year
Personal profile
Research interests
- Pathogenesis of atherosclerosis
- Treatment of increased cardiovascular risk
Specialisation
Vascular Medicine and lipoprotein metabolism
Fingerprint
Dive into the research topics where John Kastelein is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Randomized, Parallel, Open-Label, Single-Dose and Multiple-Dose Clinical Trial to Investigate the Pharmacokinetic, Pharmacodynamic, and Safety Profiles of Obicetrapib in Healthy Participants in China
Zhang, J., Cao, G., Huo, Y., Guarneri, L. L., Ditmarsch, M., Kastelein, J. J. P., Kling, D., Hsieh, A., Wuerdeman, E. & Davidson, M. H., Jan 2025, In: Journal of clinical pharmacology. 65, 1, p. 96-107 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus) -
Association Between Lipoprotein(a) and Arterial Stiffness in Young Adults with Familial Hypercholesterolemia
van den Bosch, S. E., Boer, L. M. D., Revers, A., Schrauben, E. M., Ooij, P. V., Nederveen, A. J., Corpeleijn, W. E., Kastelein, J. J. P., Wiegman, A. & Hutten, B. A., 1 Mar 2025, In: Clinical Chemistry. 14, 5, 1611.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Fixed-dose combination of obicetrapib and ezetimibe for LDL cholesterol reduction (TANDEM): a phase 3, randomised, double-blind, placebo-controlled trial
Sarraju, A., Brennan, D., Hayden, K., Stronczek, A., Goldberg, A. C., Michos, E. D., McGuire, D. K., Mason, D., Tercek, G., Nicholls, S. J., Kling, D., Neild, A. L., Kastelein, J., Davidson, M., Ditmarsch, M. & Nissen, S. E., 17 May 2025, In: The Lancet. 405, 10491, p. 1757-1768 12 p.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction
AEGIS-II Committees and Investigators & Knaapen, P., 2 May 2024, In: The New England journal of medicine. 390, 17, p. 1560-1571 12 p.Research output: Contribution to journal › Article › Academic › peer-review
63 Citations (Scopus) -
Apolipoprotein A-I infusions and cardiovascular outcomes in acute myocardial infarction according to baseline LDL-cholesterol levels: the AEGIS-II trial
Gibson, C. M., Duffy, D., Bahit, M. C., Chi, G., White, H., Korjian, S., Alexander, J. H., Lincoff, A. M., Heise, M., Kingwell, B. A., Nicolau, J. C., Lopes, R. D., Cornel, J. H., Lewis, B. S., Vinereanu, D., Goodman, S. G., Bode, C., Steg, P. G., Libby, P. & Sacks, F. M. & 38 others, , 14 Dec 2024, In: European heart journal. 45, 47, p. 5023-5038Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Citations (Scopus)1 Downloads (Pure)
Datasets
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Additional file 1 of Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis
Schmidt, A. F. (Creator), Davidson, M. H. (Creator), Ditmarsch, M. (Creator), Kastelein, J. J. (Creator) & Finan, C. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27246053, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Lower_activity_of_cholesteryl_ester_transfer_protein_CETP_and_the_risk_of_dementia_a_Mendelian_randomization_analysis/27246053
Dataset
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Additional file 1 of Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis
Schmidt, A. F. (Creator), Davidson, M. H. (Creator), Ditmarsch, M. (Creator), Kastelein, J. J. (Creator) & Finan, C. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27246053.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Lower_activity_of_cholesteryl_ester_transfer_protein_CETP_and_the_risk_of_dementia_a_Mendelian_randomization_analysis/27246053/1
Dataset
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Additional file 2 of Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis
Schmidt, A. F. (Creator), Davidson, M. H. (Creator), Ditmarsch, M. (Creator), Kastelein, J. J. (Creator) & Finan, C. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27246056.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Lower_activity_of_cholesteryl_ester_transfer_protein_CETP_and_the_risk_of_dementia_a_Mendelian_randomization_analysis/27246056/1
Dataset
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Additional file 2 of Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis
Schmidt, A. F. (Creator), Davidson, M. H. (Creator), Ditmarsch, M. (Creator), Kastelein, J. J. (Creator) & Finan, C. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27246056, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Lower_activity_of_cholesteryl_ester_transfer_protein_CETP_and_the_risk_of_dementia_a_Mendelian_randomization_analysis/27246056
Dataset