Personal profile
Research interests
Studying antibody-dependent inflammation during infection, arthritis, and (long) covid.
Specialisation
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Collaborations and top research areas from the last five years
Research output
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High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Hoepel, W., Chen, H.-J., Geyer, C. E., Allahverdiyeva, S., Manz, X. D., de Taeye, S. W., Aman, J., Mes, L., Steenhuis, M., Griffith, G. R., Bonta, P. I., Brouwer, P. J. M., Caniels, T. G., van der Straten, K., Golebski, K., Jonkers, R. E., Larsen, M. D., Linty, F., Nouta, J. & van Roomen, C. P. A. A. & 16 others, , 2 Jun 2021, In: Science translational medicine. 13, 596, eabf8654.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile20 Downloads (Pure) -
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
Amsterdam UMC COVID-19 Biobank & Amsterdam UMC COVID-19, 26 Feb 2021, In: Science. 371, 6532, abc8378.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Active control of mucosal tolerance and inflammation by human IgA and IgG antibodies
Hoepel, W., Golebski, K., van Drunen, C. M. & den Dunnen, J., Aug 2020, In: Journal of allergy and clinical immunology. 146, 2, p. 273-275 3 p.Research output: Contribution to journal › Editorial › Academic › peer-review
Open Access -
FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4
Golebski, K., Hoepel, W., van Egmond, D., de Groot, E. J., Amatngalim, G. D., Beekman, J. M., Fokkens, W. J., van Drunen, C. M. & den Dunnen, J., Mar 2019, In: Mucosal immunology. 12, 2, p. 425-433 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming
Hansen, I. S., Krabbendam, L., Bernink, J. H., Loayza-Puch, F., Hoepel, W., van Burgsteden, J. A., Kuijper, E. C., Buskens, C. J., Bemelman, W. A., Zaat, S. A. J., Agami, R., Vidarsson, G., van den Brink, G. R., de Jong, E. C., Wildenberg, M. E., Baeten, D. L. P., Everts, B. & den Dunnen, J., 2018, In: Nature communications. 9, 1, p. 863Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure)
Press/Media
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Interviewed by 'De Volkskrant' about our Long COVID research
25/03/2026
1 Media contribution
Press/Media: research
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Video interview for Dutch NOS 8 o'clock news 30 November 2025
30/11/2025
1 Media contribution
Press/Media: Press / Media
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Interviewed by 'Algemeen Dagblad' on post-COVID case report
28/06/2025
1 Media contribution
Press/Media: Press / Media
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Video interview about our ME/CFS research for International ME/CFS Conference
12/03/2026
1 Media contribution
Press/Media: interview