Projects per year
Personal profile
Research interests
My research line focuses on the development and application of advanced imaging technology for early diagnostics, therapy monitoring and prediction of various rheumatic diseases (e.g. rheumatoid arthritis, spondyloarthritis, vasculitis). In the past years, a stong focus has been put on molecular imaging and translational development of imaging markers (from lab to clinical studies) for in vivo visualization of immunological targets. Apart from diagnostics and therapy guidance, we also use these techniques for pathogenetic studies of rheumatic diseases, systemic involvement of tissues in inflammatory diseases and to support development of new therapeutic agents.
My research group currently consists of 10-15 persons (PhD students, postdoc/fellows, technicians and research nurses). The rsearch work is embedded in the EULAR network of dedicated imaging centers.
External positions
Member of scientific advisory board , Dutch Arthritis Association
Board member of working group Imaging Rheumatology of the Netherlands (IRON), Dutch Society of Rheumatology
Dutch representative in the EULAR standing committee of musculoskeletal imaging, EULAR
… → 1 Jul 2019
Keywords
- RZ Other systems of medicine
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Collaborations and top research areas from the last five years
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FOREUM career grant steinz: Muscle weakness in Rheumatoid Arthritis: more than just a decrease in muscle mass
van der Laken, J. (Principal investigator)
FOREUM Foundation for Research in Rheumatology
01/12/2024 → 31/12/2027
Project: Research
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GSK folate PET: GSK folate PET
van der Laken, J. (Principal investigator)
01/06/2019 → 31/01/2025
Project: Research
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First in man study of [18F]fluoro-PEG-folate PET: a novel macrophage imaging technique to visualize rheumatoid arthritis
Verweij, N. J. F., Yaqub, M., Bruijnen, S. T. G., Pieplenbosch, S., ter Wee, M. M., Jansen, G., Chen, Q., Low, P. S., Windhorst, A. D., Lammertsma, A. A., Hoekstra, O. S., Voskuyl, A. E. & van der Laken, C. J., 1 Dec 2020, In: Scientific reports. 10, 1, 1047.Research output: Contribution to journal › Article › Academic › peer-review
Open Access48 Citations (Scopus) -
The quantitative assessment of interstitial lung disease with positron emission tomography scanning in systemic sclerosis patients
Peelen, D. M., Zwezerijnen, B. G. J. C., Nossent, E. J., Meijboom, L. J., Hoekstra, O. S., Van der Laken, C. J. & Voskuyl, A. E., 1 Jun 2020, In: Rheumatology (Oxford, England). 59, 6, p. 1407-1415 9 p.Research output: Contribution to journal › Article › Academic › peer-review
28 Citations (Scopus) -
Implementation and role of modern musculoskeletal imaging in rheumatological practice in member countries of EULAR
Mandl, P., Ciechomska, A., Terslev, L., Baraliakos, X., Conaghan, P. G., D'Agostino, M. A., Iagnocco, A., van der Laken, C. J., Ostergaard, M. & Naredo, E., 1 Jun 2019, In: RMD open. 5, 2, e000950.Research output: Contribution to journal › Article › Academic › peer-review
Open Access30 Citations (Scopus) -
Imaging disease activity of rheumatoid arthritis by macrophage targeting using second generation translocator protein positron emission tomography tracers
Bruijnen, S. T. G., Verweij, N. J. F., Gent, Y. Y. J., Huisman, M. C., Windhorst, A. D., Kassiou, M., van de Ven, P. M., Lammertsma, A. A., Hoekstra, O. S., Voskuyl, A. E. & van der Laken, C. J., 1 Jan 2019, In: PLoS ONE. 14, 9, e0222844.Research output: Contribution to journal › Article › Academic › peer-review
Open Access19 Citations (Scopus)