Personal profile
Research interests
Inflammatory Bowel Disease, Epigenetics, DNA methylation, Immunology, Rheumatology, Microbiome, Immune-mediated diseases
Specialisation
Epigenetics in IBD
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Dive into the research topics where Ishtu Hageman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn’s disease patients identifies response-associated differences among the plasmacytoid dendritic cells and classical monocytes
Li Yim, A. Y. F., Hageman, I., Joustra, V. W., Elfiky, A. M. I. M., Ghiboub, M., Levin, E., Verhoeff, J., Verseijden, C., Admiraal, I., de Krijger, M., Wildenberg, M. E., Mannens, M., Jakobs, M. E., Kenter, S. B., Adams, A. T., Satsangi, J., D’Haens, G. R., de Jonge, W. J. & Henneman, P., 2025, In: Frontiers in immunology. 16, p. 1551017 1551017.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile31 Downloads (Pure) -
Development and validation of peripheral blood DNA methylation signatures to predict response to biological therapy in adults with Crohn's disease (EPIC-CD): an epigenome-wide association study
Joustra, V. W., Li Yim, A. Y. F., Henneman, P., Hageman, I., de Waard, T., Levin, E., Noble, A. J., Chapman, T. P., Mol, F., van Zon, S., Lee, D., McGregor, C. G. C., Hulshoff, M. S., Satsangi, J. J., de Jonge, W. J., D'Haens, G. R. & EPIC-CD Consortium, Sept 2025, In: The Lancet Gastroenterology and Hepatology. 10, 9, p. 818-830 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile116 Downloads (Pure) -
INTESTINAL TISSUE-ADHERENT MICROBIAL SIGNATURES PREDICTIVE OF RESPONSE TO ANTI-TNF-ALPHA IN CROHN'S DISEASE
Zafeiropoulou, K. (Inventor), de Jonge, W. (Inventor), D' Haens, G. (Inventor) & Hageman, I. L. (Inventor), 26 Jun 2025, IPC No. C12Q1/689, Patent No. WO2025136105A1, 26 Jun 2025, Priority date 20 Dec 2023Research output: Patent › Academic
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Peripheral blood dna methylation signatures and response to tofacitinib in moderate-To-severe ulcerative colitis
Joustra, V., Li Yim, A. Y. F., van Gennep, S., Hageman, I., de Waard, T., Levin, E., Lauffer, P., de Jonge, W., Henneman, P., Löwenberg, M. & D'Haens, G., 1 Aug 2024, In: Journal of Crohn's and Colitis. 18, 8, p. 1179-1189 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile40 Downloads (Pure) -
Novel biomarkers to guide therapy in chronic inflammatory diseases
Hageman, I. L., 2023, 280 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal