Personal profile
Research interests
The research focuses on understanding the biology of innate lymphoid cells which are important regulators and effectors of tissue immunity, homeostasis remodeling and repair. A second program is directed at optimising development of human immune system mice and a third to generate fully human monoclonal antibodies against tumor antigens
Specialisation
Immunology
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Collaborations and top research areas from the last five years
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Erratum: Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response (Immunity (2021) 54(2) (291–307.e7), (S1074761320305410), (10.1016/j.immuni.2020.12.013))
Golebski, K., Layhadi, J. A., Sahiner, U., Steveling-Klein, E. H., Lenormand, M. M., Li, R. C. Y., Bal, S. M., Heesters, B. A., Vilà-Nadal, G., Hunewald, O., Montamat, G., HeFeng, F. Q., Ollert, M., Fedina, O., Lao-Araya, M., Vijverberg, S. J. H., Maitland-van der Zee, A.-H., van Drunen, C. M., Fokkens, W. J. & Durham, S. R. & 2 others, , 12 Aug 2025, In: Immunity. 58, 8, p. 2137 1 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open AccessFile20 Downloads (Pure) -
Allergen-specific B cell responses in oral immunotherapy-induced desensitization, remission, and natural outgrowth in cow's milk allergy
Satitsuksanoa, P., van de Veen, W., Tan, G., Lopez, J.-F., Wirz, O., Jansen, K., Sokolowska, M., Mirer, D., Globinska, A., Boonpiyathad, T., Schneider, S. R., Barletta, E., Spits, H., Chang, I., Babayev, H., Tahralı, İ., Deniz, G., Yücel, E. Ö., Kıykım, A. & Boyd, S. D. & 3 others, , 2024, (E-pub ahead of print) In: Allergy: European Journal of Allergy and Clinical Immunology.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile43 Downloads (Pure) -
Cytolytic too: Granzyme B-expressing human ILC2s mediate tumor rejection
Spits, H. & Mjösberg, J., Jun 2024, In: Cell research. 34, 6, p. 403-404 2 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile28 Downloads (Pure) -
Human CD127 negative ILC2s show immunological memory
Mathä, L., Krabbendam, L., Høyer, S. M., Heesters, B. A., Golebski, K., Kradolfer, C., Ghaedi, M., Ma, J., Stadhouders, R., Bachert, C., Cardell, L.-O., Zhang, N., Holtappels, G., Reitsma, S., Helgers, L. C., Geijtenbeek, T. B. H., Coquet, J. M., Takei, F., Spits, H. & Martinez-Gonzalez, I., 5 Aug 2024, In: Journal of experimental medicine. 221, 8, e20231827.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile32 Downloads (Pure) -
Inflammatory innate lymphoid cells predict response speed to dupilumab in chronic rhinosinusitis with nasal polyps
Golebski, K., van der Lans, R. J. L., van Egmond, D., de Groot, E., Spits, H., der Zee, A.-H.M.-V., van Drunen, C. M., Fokkens, W. J. & Reitsma, S., Dec 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 12, p. 3265-3268 4 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open AccessFile27 Downloads (Pure)