Personal profile
Specialisation
Elga de Vries is a professor in Neuro-immunology and head of the Neuro-immunology research group within the department of Molecular Cell Biology and Immunology (MCBI) at the Amsterdam UMC. Her research focuses on the cross talk of the immune system and the brain and the barriers between them. Using state of the art techniques, she and her team aim to uncover in predominantly human in vitro systems, samples and post-mortem tissues such underlying mechanisms, with a focus on multiple sclerosis (MS) and Alzheimer’s disease.
Elga de Vries was trained in the field of neuroscience/neuro-immunology as a biomedical scientist at the University of Utrecht (1990-1995) and during her PhD at Leiden University (1990-1995) and post-doc (as Marie-Curie fellow; 1998-1999) at University College London. Since 2000 (2011 as full professor), she runs her Neuro-immunology research group at the MCBI. As a PI and co-PI, she manage(d) various projects of PhD students, post-docs and research technicians (supervision: 21 completed PhD projects, 9 ongoing PhD projects, 3 ongoing postdoc projects, 6 completed postdoc projects, 2 technicians). Her work is/has been funded by the Dutch MS Research Foundation, ZonMW, NWO (VIDI in 2004), Health Holland and the EU (i.e. Marie Cure ITN, IMI, H2020 program). Her work is internationally recognized by peers as evidenced by the high number of collaborative grants and invitations for keynote lectures. Her work is published in leading journals such as ACTA Neuropathologica, eLife, Nature Neuroscience and Fluids and Barriers of the CNS. Elga de Vries is also scientific director of the MSCA and task force member of the research program Neuro-infection and Neuro-inflammation of the research institute Amsterdam Neuroscience, in which her research is embedded. She also serves as president-elect of the International Brain Barrier Society (https://www.ibbsoc.org/) and as chair of BBBNedwork (http://www.bbbnedwork.nl/), and as an active member of the scientific advisory board of Alzheimer Nederland and of the editorial board of the journal Fluids and Barriers of the CNS.
External positions
Member scientific advisory board, Alzheimer Nederland, Amersfoort, Netherlands
… → 1 Jan 2025
Member scientific advisory board, BPRC, Rijswijk
… → 1 Apr 2025
Keywords
- R Medicine (General)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis
Rodríguez-Lorenzo, S., van Olst, L., Rodriguez-Mogeda, C., Kamermans, A., van der Pol, S. M. A., Rodríguez, E., Kooij, G. & de Vries, H. E., 2022, In: eLife. 11, e73849.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile23 Downloads (Pure) -
Breaching Brain Barriers: B Cell Migration in Multiple Sclerosis
Rodriguez-Mogeda, C., Rodríguez-Lorenzo, S., Attia, J., van Horssen, J., Witte, M. E. & de Vries, H. E., 7 Jun 2022, In: Biomolecules. 12, 6, 800.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile22 Downloads (Pure) -
Brain Pericytes and Wnt/β-Catenin Signaling Induce Functional Blood-Brain Barrier Phenotype in Human iPSC-Derived Model
Nogueira Pinto, H., Kok, N. R., Hauger, P. C., Karsten-van Diepen, M., de Kok, M., Paauw, N. J., van der Pol, S. M. A., Nugteren-Boogaard, J. P., Hordijk, P. L., Beekhuis-Hoekstra, S. D., Gibbs, S., de Wit, N. M. & de Vries, H. E., 28 Jan 2026, (E-pub ahead of print) In: Small methods. p. e02114Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Fatty acid binding protein 2 (FATP2/SLC27A2) blockade with Lipofermata elicits dual effects on inflammatory responses in human monocytes and macrophages
Hahn, N., Chornyi, S., Heister, D., de Vries, H. E., Giera, M., Boon, M. R., Kooij, G. & van den Bossche, J., 1 Feb 2026, In: Immunology letters. 277, 107092.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile30 Downloads (Pure) -
Adult human subventricular zone microglia promote a pro-neurogenic niche for neuronal progenitors in Parkinson's disease
Pecoraro, S., Verkerke, M., Sluijs, J. A., van het Hof, B., van der Pol, S. M. A., van Strien, M. E., van der Kant, R., de Vries, C., de Vries, H. E., van de Berg, W. D. J., Hol, E. M. & Donega, V., 1 Oct 2025, In: Brain, behavior, and immunity. 129, p. 318-334 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile24 Downloads (Pure)
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Immune events at the brain barriers
de Vries, E. (Keynote speaker)
30 Nov 2022Activity: Talk or presentation › Invited talk › Academic
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Immune events at the Brain Barriers
de Vries, E. (Keynote speaker)
7 Nov 2022Activity: Talk or presentation › Invited talk › Academic
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ECTRIMS
de Vries, E. (Organiser)
26 Oct 2022Activity: Participating in or organising an event › organising
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Scientific highlights
de Vries, E. (Invited speaker)
26 Oct 2022Activity: Talk or presentation › Invited talk › Academic
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Signalling at the Brain Barriers
de Vries, E. (Member of programme committee)
22 Sept 2022Activity: Participating in or organising an event › organising
Prizes
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Grant for MS Innovation
Rijnsburger, M. (Recipient) & de Vries, E. (Recipient), 7 Aug 2020
Prize › Academic
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Grant for MS Innovative research
de Vries, E. (Recipient), 1 Sept 2015
Prize: Honorary award › Academic
Press/Media
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Expert view on drug delivery across the blood-brain barrier
13/10/2021
1 Media contribution
Press/Media: exportcomment
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