Projects per year
Personal profile
Specialisation
Elga de Vries is a professor in Neuro-immunology and head of the Neuro-immunology research group within the department of Molecular Cell Biology and Immunology (MCBI) at the Amsterdam UMC. Her research focuses on the cross talk of the immune system and the brain and the barriers between them. Using state of the art techniques, she and her team aim to uncover in predominantly human in vitro systems, samples and post-mortem tissues such underlying mechanisms, with a focus on multiple sclerosis (MS) and Alzheimer’s disease.
Elga de Vries was trained in the field of neuroscience/neuro-immunology as a biomedical scientist at the University of Utrecht (1990-1995) and during her PhD at Leiden University (1990-1995) and post-doc (as Marie-Curie fellow; 1998-1999) at University College London. Since 2000 (2011 as full professor), she runs her Neuro-immunology research group at the MCBI. As a PI and co-PI, she manage(d) various projects of PhD students, post-docs and research technicians (supervision: 21 completed PhD projects, 9 ongoing PhD projects, 3 ongoing postdoc projects, 6 completed postdoc projects, 2 technicians). Her work is/has been funded by the Dutch MS Research Foundation, ZonMW, NWO (VIDI in 2004), Health Holland and the EU (i.e. Marie Cure ITN, IMI, H2020 program). Her work is internationally recognized by peers as evidenced by the high number of collaborative grants and invitations for keynote lectures. Her work is published in leading journals such as ACTA Neuropathologica, eLife, Nature Neuroscience and Fluids and Barriers of the CNS. Elga de Vries is also scientific director of the MSCA and task force member of the research program Neuro-infection and Neuro-inflammation of the research institute Amsterdam Neuroscience, in which her research is embedded. She also serves as president-elect of the International Brain Barrier Society (https://www.ibbsoc.org/) and as chair of BBBNedwork (http://www.bbbnedwork.nl/), and as an active member of the scientific advisory board of Alzheimer Nederland and of the editorial board of the journal Fluids and Barriers of the CNS.
External positions
Member scientific advisory board, Alzheimer Nederland, Amersfoort, Netherlands
… → 1 Jan 2025
Member scientific advisory board, BPRC, Rijswijk
… → 1 Apr 2025
Keywords
- R Medicine (General)
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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MicroRNAs, novel tools for treatment ofmultiple sclerosis
de Vries, H. (Principal investigator)
National Multiple Sclerosis Society
01/10/2012 → 30/09/2013
Project: Research
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Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis
Rodríguez-Lorenzo, S., van Olst, L., Rodriguez-Mogeda, C., Kamermans, A., van der Pol, S. M. A., Rodríguez, E., Kooij, G. & de Vries, H. E., 2022, In: eLife. 11, e73849.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Citations (Scopus) -
Breaching Brain Barriers: B Cell Migration in Multiple Sclerosis
Rodriguez-Mogeda, C., Rodríguez-Lorenzo, S., Attia, J., van Horssen, J., Witte, M. E. & de Vries, H. E., 7 Jun 2022, In: Biomolecules. 12, 6, 800.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access16 Citations (Scopus) -
Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction
Hansen, C. E., Vacondio, D., van der Molen, L., Jüttner, A. A., Fung, W. K., Karsten, M., van het Hof, B., Fontijn, R. D., Kooij, G., Witte, M. E., Roks, A. J. M., de Vries, H. E., Mulder, I. & de Wit, N. M., 1 Dec 2025, In: Cell death & disease. 16, 1, 1.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
The gut-brain-axis one year after treatment with cladribine tablets in patients with relapsing remitting multiple sclerosis: a pilot study
van Pamelen, J., Rodriguez-Mogeda, C., van Olst, L., van der Pol, S. M. A., Boon, M. L., de Beukelaar, J. & BIA Study Group, 2025, In: Frontiers in immunology. 16, 1514762.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Vascularized human brain organoids: current possibilities and prospects
Kistemaker, L., van Bodegraven, E. J., de Vries, H. E. & Hol, E. M., 2025, (E-pub ahead of print) In: Trends in biotechnology.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access2 Citations (Scopus)
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Immune events at the brain barriers
de Vries, E. (Keynote speaker)
30 Nov 2022Activity: Talk or presentation › Invited talk › Academic
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Immune events at the Brain Barriers
de Vries, E. (Keynote speaker)
7 Nov 2022Activity: Talk or presentation › Invited talk › Academic
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ECTRIMS
de Vries, E. (Organiser)
26 Oct 2022Activity: Participating in or organising an event › organising
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Scientific highlights
de Vries, E. (Invited speaker)
26 Oct 2022Activity: Talk or presentation › Invited talk › Academic
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Signalling at the Brain Barriers
de Vries, E. (Member of programme committee)
22 Sept 2022Activity: Participating in or organising an event › organising
Prizes
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Grant for MS Innovation
Rijnsburger, M. (Recipient) & de Vries, E. (Recipient), 7 Aug 2020
Prize › Academic
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Grant for MS Innovative research
de Vries, E. (Recipient), 1 Sept 2015
Prize: Honorary award › Academic
Press/Media
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Expert view on drug delivery across the blood-brain barrier
13/10/2021
1 Media contribution
Press/Media: exportcomment
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