Personal profile
Research interests
Personalized treatement.
We performe translational and clinical research on the pathogenesis and treatment of inflammatory rheumatic diseases. We try to answer questions raised by the clinical follow up of patients at Reade using the moleculair immunological knowledge from the departement immunopathology at Sanquin. Our group is recognized as expert in the field of immunogenicity of biologicals and therapeutic drug monitoring.
Specialisation
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Collaborations and top research areas from the last five years
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Adalimumab serum concentration to choose a subsequent biological DMARD in patients with rheumatoid arthritis (ADDORA-switch): results of a blinded randomised test-treatment trial
Wientjes, M. H. M., Atiqi, S., Wolbink, G. J., Nurmohamed, M. T., Boers, M., Hooijberg, F., Rispens, T., de Vries, A., van Vollenhoven, R. F., Ramiro, S., van Herwaarden, N., van den Bemt, B. J. F. & den Broeder, A. A., Aug 2025, In: Annals of the rheumatic diseases. 84, 8, p. 1293-1300 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Different rheumatoid factor binding patterns distinguish between Sjögren's disease with or without associated RA
Oskam, N., Verstappen, G., Derksen, N. I. L., Ooijevaar-de Heer, P., Bootsma, H., Wolbink, G., Kroese, F. & Rispens, T., 22 Jun 2025, In: RMD open. 11, 2, e005386.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Downloads (Pure) -
Evolution of SARS-CoV-2 antibody repertoire after successive mRNA vaccinations under immunosuppressive treatment
T2B! immunity against SARS-CoV-2 study group, Bemelman, F. J. & Hilhorst, M. L., Mar 2025, In: EBioMedicine. 113, p. 105620 105620.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile20 Downloads (Pure) -
Impact of COVID-19 disease and vaccination on dermatological immune-mediated inflammatory diseases atopic dermatitis, psoriasis, and vitiligo: a Target2B! substudy
van Buchem-Post, N. F., Ouwerkerk, W., Stalman, E. W., van Dam, K. P. J., Wieske, L., Bekkenk, M. W., Wolkerstorfer, A., Spuls, P., Musters, A. H., Bosma, A. L., Hijnen, D.-J., Eftimov, F., Luiten, R. M., T2B! immunity against SARS-CoV-2 study group & Hilhorst, M. L., Apr 2025, In: Journal of dermatology. 52, 4, p. 624-633 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile24 Downloads (Pure) -
Pharmacokinetic Model-Informed Precision Dosing of Natalizumab in Multiple Sclerosis
van den Berg, S. P. H., Toorop, A. A., Hooijberg, F., Wolbink, G., Voelkner, N. M. F., Gelissen, L. M. Y., Killestein, J., van Kempen, Z. L. E., Dorlo, T. P. C. & Rispens, T., Jun 2025, In: CPT: Pharmacometrics and Systems Pharmacology. 14, 6, p. 1032-1041 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile24 Downloads (Pure)