Projects per year
Personal profile
Specialisation
Multiple Sclerosis, Ethiology, Myelin, Neurodegeneration, Axo-Myelinic Synapse
Research interests
As a neuroscientist I am passionate about the brain. Two central research questions, from which numerous smaller questions are derived, are
1) How does multiple sclerosis start?
2) What happens in the brain at a cellular and molecular level when (MS) patients show imaging-measured network changes and concomitant cognitive deterioration?
Both questions are helping us to understand (MS) disease mechanisms in more detail, with the eventual aim of designing curative therapies.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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PJT-191816 Microglia Remyelin.: Aging impairs microglial phagocytosis and stalls remyelination CIHR PJT-191816
van der Werf, Y. (Principal investigator) & Schenk, G. (Project Leader)
01/04/2024 → 31/03/2029
Project: Research
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The Forgotten Brother: The Forgotten Brother: The lnvolvement of The lnnate Bl-cell Subsets in Multiple Sclerosis and Neurodegeneration
Schoonheim, M. (Principal investigator) & Schenk, G. (Project Leader)
NWO: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
08/11/2022 → 07/11/2026
Project: Research
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define microglia: Define the phenotype and function of regeneration-associated microglia along the continuum of remyelination
Schoonheim, M. (Principal investigator) & Schenk, G. (Project Leader)
01/10/2019 → 30/09/2024
Project: Research
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Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy
Meijns, N. R. C., Blokker, M., Idema, S., t Hart, B. A., Veta, M., Ettema, L., van Iersel, J., Zhang, Z., Schenk, G. J., Groot, M. L. & Luchicchi, A., 1 Mar 2025, In: PLoS ONE. 20, 3 March, e0310663.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
Thalamic atrophy in multiple sclerosis is associated with tract disconnection and altered microglia
Rodriguez-Mogeda, C., Koubiyr, I., Prouskas, S. E., Georgallidou, M., van der Pol, S. M. A., Fernandez, R. F., de Graaf, Y. G., van der Werf, Y. D., Jonkman, L. E., Schenk, G. J., Barkhof, F., Hulst, H. E., Witte, M. E., Schoonheim, M. M. & de Vries, H. E., 1 Jun 2025, In: Acta Neuropathol.. 149, 1, 52.Research output: Contribution to journal › Article › Academic › peer-review
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Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: Results from REDUCE-IT
Burger, P. M., Bhatt, D. L., Dorresteijn, J. A. N., Koudstaal, S., Mosterd, A., Martens, F. M. A. C., Steg, P. G., Visseren, F. L. J. & REDUCE-IT Investigators, 1 Sept 2024, In: European Heart Journal - Cardiovascular Pharmacotherapy. 10, 6, p. 488-499 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Micro-diffusely abnormal white matter: An early multiple sclerosis lesion phase with intensified myelin blistering
Luchicchi, A., Muñoz-Gonzalez, G., Halperin, S. T., Strijbis, E., van Dijk, L. H. M., Foutiadou, C., Uriac, F., Bouman, P. M., Schouten, M. A. N., Plemel, J., 't Hart, B. A., Geurts, J. J. G. & Schenk, G. J., 1 Apr 2024, In: Annals of clinical and translational neurology. 11, 4, p. 973-988 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Downloads (Pure) -
Inhibitory synaptic loss drives network changes in multiple sclerosis: An ex vivo to in silico translational study
Huiskamp, M., Kiljan, S., Kulik, S., Witte, M. E., Jonkman, L. E., GJM Bol, J., Schenk, G. J., Hulst, H. E., Tewarie, P., Schoonheim, M. M. & Geurts, J. J. G., Nov 2022, In: MULTIPLE SCLEROSIS JOURNAL. 28, 13, p. 2010-2019 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure)