Projects per year
Personal profile
Research interests
Frederik Barkhof received his MD from VU University, Amsterdam (NL) in 1988 and defended his PhD thesis in 1992, for which he received the Philips Prize for Radiology (1992) and the Lucien Appel Prize for Neuroradiology (1994). Since 2001 he serves as a full Professor in Neuroradiology at the department of Radiology & Nuclear Medicine at VUmc. In 2015 he was appointed as full Professor of Neuroradiology at institutes of Biomedical Engineering and Neurology at UCL in London (UK) to translate novel imaging techniques. In 2018 he received the John Dystel prize by the US National MS Society and the American Academy of Neurology outstanding contributions to research in MS. In 2019, he became a senior fellow of the ISMRM
Prof. Barkhof was the chairman of the Dutch Society of Neuroradiology and the MAGNIMS study group for many years. He is leading the Queen Square MS Centre Trial Unit, involved in analysis of multicentre drug trials. He serves on the Editorial boards of Radiology, Brain, Multiple Sclerosis Journal, Neuroradiology and Neurology. He is a fellow of the Royal College of Radiology.
His research interests focus on childhood white matter disease, multiple sclerosis, ageing and dementia. He (co)authored >1100 papers referenced in PubMed, has an H-factor of 164 (Google Scholar) with >110,000 citations and is listed among 3000 most influential scientists world-wide by Thompson-Reuters. He is the author of the books “Neuroimaging in Dementia”, “Clinical applications of functional brain MRI” and “Clinical Neuroradiology – the ESNR textbook”
Cumulatively, he has received >30 million euro grant money from various national and international funding agencies and performed contract research for all major pharmaceutical companies with cumulative contract value of >15 million euro. More than 40 PhD students graduated under his supervision and 5 of them have subsequently attained a full professorship
Related documents
External positions
Professor of Neuroradiology, UCL Institute of Neurology
Collaborations and top research areas from the last five years
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EPSRC Centre for Doctoral Training in Intelligent, Integrated Imaging In Healthcare (i4health)
Zhang, H. H. (Principal investigator), Alexander, D. D. (CoPI), Barkhof, F. (CoPI), Punwani, S. S. (CoPI), Thielemans, K. F. J. J. K. F. J. J. (CoPI), Denaxas, S. S. (CoPI), Blandford, A. A. (CoPI), Drobnjak, I. I. (CoPI), Hebden, J. C. J. C. (CoPI) & Clarkson, M. J. M. J. (CoPI)
Engineering and Physical Sciences Research Council
30/09/2019 → 30/03/2028
Project: Research
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Harmonization of acquisition and processing of brain imaging biomarkers for neurodegenerative diseases: a strategic research agenda for best-practice guidelines
Frisoni, G. B. G. B. (Principal investigator), Drinkenburg, W. H. W. H. (CoPI), Hort, J. J. (CoPI), Nedelska, Z. Z. (CoPI), Chupin, M. M. (CoPI), Habert, M.-O.M.-O. (CoPI), Mangin, J.-F.J.-F. (CoPI), Payoux, P. P. (CoPI), Drzezga, A. A. (CoPI), Mulert, C. H. T. C. H. T. (CoPI), Teipel, S. S. (CoPI), Babiloni, C. C. (CoPI), Nobili, F. F. (CoPI), Jovicich, J. J. (CoPI), Barkhof, F. (CoPI), Van Berckel, B. B. (CoPI), Fladby, T. T. (CoPI), Aarsland, D. D. (CoPI), Berlot, R. R. (CoPI), Jelic, V. V. (CoPI), Nordberg, A. A. (CoPI), Westman, E. E. (CoPI), Garibotto, V. V. (CoPI), Murray, M. M. M. M. (CoPI), Emek-savas, D. D. D. D. (CoPI), Yener, G. G. G. G. (CoPI), Herholz, K. K. (CoPI), Mackay, C. C. (CoPI), Scahill, R. I. R. I. (CoPI) & Thomas, D. L. D. L. (CoPI)
EU Joint Programme – Neurodegenerative Disease Research
01/01/2016 → …
Project: Research
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ChariotMS - Cladribine to halt deterioration in people with advanced multiple sclerosis
Schmierer, K. K. (Principal investigator), Ford, H. H. (CoPI), Hussain, T. T. (CoPI), Chapman, C. C. (CoPI), Mihaylova, B. B. (CoPI), Baker, D. D. (CoPI), Barkhof, F. (CoPI), Giovannoni, G. G. (CoPI), Chataway, J. J. (CoPI), Hobart, J. J. (CoPI), Hooper, R. R. (CoPI), Chandran, S. S. (CoPI) & Pavitt, S. S. (CoPI)
National Institute for Health and Care Research
01/04/2020 → 31/01/2025
Project: Research
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Chronically active lesions - novel MRI markers
Barkhof, F. (Principal investigator)
01/01/2020 → 31/12/2022
Project: Research
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“Dirty” Virchow-Robin Spaces in Controls and Multiple Sclerosis - Histological Validation of a Novel MRI Feature -
Barkhof, F. (Principal investigator)
01/01/2020 → 31/12/2020
Project: Research
Research output
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A 50-year data-driven model of disability and lesion load trajectories in progressive multiple sclerosis
Oxtoby, N. P. & Barkhof, F., 2025, In: Brain Communications. 7, 1, fcae474.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open Access -
Alzheimer Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for Monitoring of Amyloid-Related Imaging Abnormalities
Cogswell, P. M., Andrews, T. J., Barakos, J. A., Barkhof, F., Bash, S., Daniel Benayoun, M., Chiang, G. C., Franceschi, A. M., Jack, C. R., Pillai, J. J., Poussaint, T. Y., Raji, C. A., Ramanan, V. K., Tanabe, J., Tanenbaum, L., Whitlow, C. T., Yu, F. F. & ASNR Alzheimer, ARIA, and Dementia Study Group, 1 Jan 2025, In: American Journal of Neuroradiology. 46, 1, p. 24-32 9 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access8 Citations (Scopus) -
A Machine Learning Model to Harmonize Volumetric Brain MRI Data for Quantitative Neuroradiologic Assessment of Alzheimer Disease
Archetti, D., Venkatraghavan, V., Weiss, B. L., Bourgeat, P., Auer, T., Vidnyánszky, Z., Durrleman, S., van der Flier, W. M., Australian Imaging, Biomarker and Lifestyle Study, Alzheimer’s Disease Neuroimaging Initiative & E-DADS (Early Detection of Alzheimer’s Disease Subtypes) Consortium, 1 Jan 2025, In: Radiology: Artificial Intelligence. 7, 1, e240030.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
Amyloid-Related Imaging Abnormalities (ARIA) in Clinical Trials of Gantenerumab in Early Alzheimer Disease
Salloway, S., Wojtowicz, J., Voyle, N., Lane, C. A., Klein, G., Lyons, M., Rossomanno, S., Mazzo, F., Bullain, S., Barkhof, F., Bittner, T., Schneider, A., Grundman, M., Aldea, R., Boada, M., Smith, J. & Doody, R., 13 Jan 2025, In: JAMA Neurology. 82, 1, p. 19-29 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Amyloid-β deposition predicts oscillatory slowing of magnetoencephalography signals and a reduction of functional connectivity over time in cognitively unimpaired adults
Scheijbeler, E. P., de Haan, W., Coomans, E. M., den Braber, A., Tomassen, J., ten Kate, M., Konijnenberg, E., Collij, L. E., van de Giessen, E., Barkhof, F., Visser, P. J., Stam, C. J. & Gouw, A. A., 2025, In: Brain Communications. 7, 1, fcaf018.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus)
Prizes
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