I lead the AUMC expert clinic for familial and hereditary polyposis and colorectal cancer (CRC), and am medical director of the Bergman IZA expertise center for endoscopy. I combine my clinical work as a gastroenterologist with clinical and translational research, chairing the CRC research group at the AUMC Gastroenterology & Hepatology department since 2005. My research group focuses on CRC screening and surveillance, both in average risk and high-risk populations (eg. hereditary polyposis and cancer syndrome patients). My research work includes quality and advanced techniques in colonoscopy and endoscopic treatment modalities for gastrointestinal polyps and early CRC. I have been one of the frontrunners for the Dutch national CRC screening program, and I am still involved in the program's evaluation and quality assurance. I am currently global chair of the CRC screening committee of the World Endoscopy Organisation. In addition, I am a member of multiple national and international working groups and guideline committees on CRC screening, CRC surveillance, colonoscopy quality, advanced endoscopic imaging, endoscopist training, and management of hereditary CRC syndromes.

Gastrointestinal Oncology. Special interest in colorectal screening and diagnosis both in average risk populations (in CRC screening program) and high-risk populations such as hereditary polyposis and cancer syndrome patients (ao. Lynch syndrome, Familial adenomatous polyposis (FAP), MYH-associated polyposis (MAP), Serrated polyposis syndrome (SPS). Peutz-Jeghers syndrome).