Personal profile
Research interests
My goal is to understand the molecular mechanisms that regulate blood-retina barrier (BRB) function during health and disease. During my project, l have a special interest in the role of the endothelial cell-specific protein PLVAP in microvascular permeability.
Background: Biomedical Sciences, with a focus on advanced microscopy
Specialisation
Endothelial cell function ; Microvascular permeability
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Dive into the research topics where Esmeralda Bosma is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Trends and epidemiology of children treated in specialized burn centers in the Netherlands between 2009 and 2022
Dutch Burn Repository group, 2 Jan 2025, In: European journal of pediatrics. 184, 1, p. 114 114.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile56 Downloads (Pure) -
Quantitative Assessment of the Apical and Basolateral Membrane Expression of VEGFR2 and NRP2 in VEGF-A-stimulated Cultured Human Umbilical Vein Endothelial Cells
Bosma, E. K., Darwesh, S., Zheng, J. Y., van Noorden, C. J. F., Schlingemann, R. O. & Klaassen, I., 1 Aug 2022, In: journal of histochemistry and cytochemistry. 70, 8, p. 557-569 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile21 Downloads (Pure) -
Microvascular Complications in the Eye: Diabetic Retinopathy
Bosma, E. K., van Noorden, C. J. F., Klaassen, I. & Schlingemann, R. O., 29 Oct 2018, Diabetic Nephropathy: Pathophysiology and Clinical Aspects. Springer International Publishing, p. 305-321 (Diabetic Nephropathy: Pathophysiology and Clinical Aspects).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
Open AccessFile21 Downloads (Pure) -
The role of plasmalemma vesicle-associated protein in pathological breakdown of blood-brain and blood-retinal barriers: Potential novel therapeutic target for cerebral edema and diabetic macular edema
Bosma, E. K., van Noorden, C. J. F., Schlingemann, R. O. & Klaassen, I., 2018, In: Fluids and barriers of the CNS. 15, 1, 24.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile15 Downloads (Pure) -
The balance between Gαi-Cdc42/Rac and Gα12/13-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate
Reinhard, N. R., Mastop, M., Yin, T., Wu, Y., Bosma, E. K., Gadella, T. W. J., Goedhart, J. & Hordijk, P. L., 7 Nov 2017, In: Molecular biology of the cell. 28, 23, p. 3371-3382 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile36 Downloads (Pure)