Projects per year
Personal profile
Research interests
I obtained my PhD in Advanced Hemodynamic Modelling at the Department of Anesthesiology of Amsterdam UMC and currently work as a postdoctoral researcher. I am a Technical Physician with a strong focus on translating complex physiological data into clinically actionable insights.
My work centers on the development of machine learning–based algorithms to estimate the probability of individuals having a disease (diagnostic applications) or developing a disease or health state over time (prognostic applications). By combining physiological modeling with clinical data, the goal is to support more accurate and timely clinical decision-making.
My research is embedded within the Anesthesiology and Intensive Care departments, where continuous monitoring, hemodynamics, and critical care medicine converge. The focus lies on developing robust, interpretable, and clinically applicable models that can be deployed in real-world, high-acuity clinical settings.
A key objective of this work is to bridge the gap between technical innovation and clinical practice by translating advances in machine learning and computational modeling into practical tools that integrate seamlessly into clinical workflows and ultimately improve patient outcomes.
Specialisation
Hemodynamics, Cerebral autoregulation, Machine learning, Modeling
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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PuO2: Urinary Oxygenation Monitoring Perioperatively
Hulst, B. (Project Leader), Oosterom - Eijmael, M. (Internal PhD candidate), van Zwol, J. (Internal PhD candidate), Hemmes, S. (Project Member), Kho, E. (Project Member) & Veelo, D. (Project Member)
BJA-ESAIC, Amsterdam Cardiovascular Science (ACS)
01/05/2022 → …
Project: Research
Research output
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Cerebral hemodynamics during sustained intraoperative hypotension
Kho, E., Sperna Weiland, N. H., Vlaar, A. P. J., Veelo, D. P., van der Ster, B. J. P., Corsmit, O. T., Koolbergen, D. R., Dilai, J. & Immink, R. V., 1 Jun 2022, In: Journal of applied physiology (Bethesda, Md.. 132, 6, p. 1560-1568 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile95 Downloads (Pure) -
Detecting aortic valve stenosis based on the non-invasive blood pressure waveform—a proof of concept study
Kho, E., Schenk, J., Vlaar, A. P. J., Vis, M. M., Wijnberge, M., Stam, L. B., van Mourik, M., Jorstad, H. T., Hermanns, H., Westerhof, B. E., Veelo, D. P. & van der Ster, B. J. P., Dec 2024, In: Geroscience. 46, 6, p. 5955-5965 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile19 Downloads (Pure) -
Defining Postinduction Hemodynamic Instability With an Automated Classification Model
Kho, E., Immink, R. V., van der Ster, B. J. P., van der Ven, W. H., Schenk, J., Hollmann, M. W., Tol, J. T. M., Terwindt, L. E., Vlaar, A. P. J. & Veelo, D. P., 2024, (E-pub ahead of print) In: Anesthesia and analgesia. 10.1213/ANE.0000000000007315.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile67 Downloads (Pure) -
Regulation of cerebrovascular resistance below the lower limit of cerebral autoregulation during induced hypotension: an observational study
Kho, E., van den Dool, R. E. C., Mahes, S. S., Corsmit, O. T., Vlaar, A. P. J., Koolbergen, D. R., Veelo, D. P., Sperna Weiland, N. H. & Immink, R. V., Apr 2025, In: British journal of anaesthesia. 134, 4, p. 1009-1017 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile60 Downloads (Pure) -
Machine learning in mitral valve repair: promise, precision, and the challenge of clinical translation
Kho, E., Oudeman, M. A. P., Hermanns, H. & Veelo, D. P., 31 Aug 2026, In: Journal of thoracic disease. 18, 8, 984.Research output: Contribution to journal › Editorial › Academic › peer-review
Open AccessFile