Personal profile
Research interests
I obtained my PhD in Advanced Hemodynamic Modelling at the Department of Anesthesiology of Amsterdam UMC and currently work as a postdoctoral researcher. I am a Technical Physician with a strong focus on translating complex physiological data into clinically actionable insights.
My work centers on the development of machine learning–based algorithms to estimate the probability of individuals having a disease (diagnostic applications) or developing a disease or health state over time (prognostic applications). By combining physiological modeling with clinical data, the goal is to support more accurate and timely clinical decision-making.
My research is embedded within the Anesthesiology and Intensive Care departments, where continuous monitoring, hemodynamics, and critical care medicine converge. The focus lies on developing robust, interpretable, and clinically applicable models that can be deployed in real-world, high-acuity clinical settings.
A key objective of this work is to bridge the gap between technical innovation and clinical practice by translating advances in machine learning and computational modeling into practical tools that integrate seamlessly into clinical workflows and ultimately improve patient outcomes.
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Collaborations and top research areas from the last five years
Research output
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Differences in incidence of post-induction hypotension depending on the time of day: a post-hoc propensity score matched analysis
Tol, J. T. M., Meewisse, A. J. G., Noteboom, S. H., van der Ven, W. H., Kurucz, V. C., Terwindt, L. E., Kho, E., van der Ster, B., Vlaar, A. P. J., Stenvers, D. J., Hermanides, J., van Zuylen, M. L., Veelo, D. P. & Schenk, J., 1 Nov 2025, In: Journal of clinical anesthesia. 107, 111984.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile53 Downloads (Pure) -
From intensive care monitors to cloud environments: a structured data pipeline for advanced clinical decision support
Noteboom, S. H., Kho, E., Galanty, M., Sánchez, C. I., ten Bookum, F. C. P., Veelo, D. P., Vlaar, A. P. J. & van der Ster, B. J. P., 1 Jan 2025, In: EBioMedicine. 111, 105529.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile33 Downloads (Pure) -
Interpretation of Viscoelastic Hemostatic Assays in Cardiac Surgery Patients: Importance of Clinical Context
Noteboom, S. H., Kho, E., Veelo, D. P., van der Ster, B. J. P., van Haeren, M. M. T., Viersen, V. A., Müller, M. C. A., Hermanns, H., Vlaar, A. P. J. & Schenk, J., 1 Sept 2025, In: Anesthesia and analgesia. 141, 3, p. 588-597 10 p., 10.1213/ANE.0000000000007400.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile36 Downloads (Pure) -
Pre-operative reference ranges for ROTEM® sigma in patients undergoing cardiac surgery: a secondary analysis of two prospective trial cohorts
van Haeren, M. M. T., Brouwers, M., Schenk, J., Breel, J. S., Noteboom, S. H., Kho, E., Eberl, S., Veelo, D. P., Vlaar, A. P. ., Müller, M. C. A. & Hermanns, H., Aug 2025, In: Anaesthesia. 80, 8, p. 935-945 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile34 Downloads (Pure) -
Regulation of cerebrovascular resistance below the lower limit of cerebral autoregulation during induced hypotension: an observational study
Kho, E., van den Dool, R. E. C., Mahes, S. S., Corsmit, O. T., Vlaar, A. P. J., Koolbergen, D. R., Veelo, D. P., Sperna Weiland, N. H. & Immink, R. V., Apr 2025, In: British journal of anaesthesia. 134, 4, p. 1009-1017 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Downloads (Pure)