Research output per year
Research output per year
Personal profile
Research interests
Elena Levtchenko focuses her research on unravelling disease mechanisms and finding the best treatments for children with genetic kidney disorders and kidney failure. She has developed a non-invasive methodology for deriving human kidney cells from uirne of the patients and healthy people allowing to establish novel models and testing new therapies.
Dr. Levtchenko has devoted her carreer to nephropathic cystinosis, a rare lysosomal storage disease, primary affecting the kidney. More recently, she discovered a new type of kidney stem cells that can be isolated from urine of preterm neonates who were born before the completion of nephrogenesis and has shown that these cells have potential to regenerate adult kidneys.
Specialisation
Pediatric nephrology, Genetic kidney diseases, Metabolic kidney diseases, Cystinosis, Renal tubular diseases, Kidney transplantation, Kidney regeneration, Kidney stem cells, Gene therapy
Keywords
- R Medicine (General)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells
Arcolino, F. O., Hosgood, S., Akalay, S., Jordan, N., Herman, J., Elliott, T., Veys, K., Vermeire, K., Sprangers, B., Nicholson, M., van den Heuvel, L. & Levtchenko, E., 1 Dec 2022, In: American journal of transplantation. 22, 12, p. 2791-2803Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Downloads (Pure) -
Chitotriosidase as a novel biomarker for therapeutic monitoring of nephropathic cystinosis
Veys, K. R. P., Elmonem, M. A., Van Dyck, M., Janssen, M. C., Cornelissen, E. A. M., Hohenfellner, K., Prencipe, G., Van Den Heuvel, L. P. & Levtchenko, E., May 2020, In: Journal of the American Society of Nephrology. 31, 5, p. 1092-1106 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile18 Downloads (Pure) -
Allogeneic HSCT transfers wild-type cystinosin to nonhematological epithelial cells in cystinosis: First human report
Elmonem, M. A., Veys, K., Oliveira Arcolino, F., Van Dyck, M., Benedetti, M. C., Diomedi-Camassei, F., De Hertogh, G., van den Heuvel, L. P., Renard, M. & Levtchenko, E., Nov 2018, In: American journal of transplantation. 18, 11, p. 2823-2828 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Cystinuria: clinical practice recommendation
Metabolic Nephropathy Workgroup of the European Reference Network for Rare Kidney Diseases (ERKNet) and eUROGEN, Jan 2021, In: Kidney international. 99, 1, p. 48-58 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Downloads (Pure) -
Urine of preterm neonates as a novel source of kidney progenitor cells
Arcolino, F. O., Zia, S., Held, K., Papadimitriou, E., Theunis, K., Bussolati, B., Raaijmakers, A., Allegaert, K., Voet, T., Deprest, J., Vriens, J., Toelen, J., Van Den Heuvel, L. & Levtchenko, E., 2016, In: Journal of the American Society of Nephrology. 27, 9, p. 2762-2770 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Downloads (Pure)
Activities
- 1 Oral presentation
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Inaugural Lecture for Obtaining Professor Title in Translational Pediatric Nephrology in the University of Amsterdam
Levtchenko, E. (Speaker)
6 Dec 2023Activity: Talk or presentation › Oral presentation › Academic
File
Prizes
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Clinical Investigator of FWO (Flemish Foundation of Scientific Research); 2009-2014, 2014-2019, 2019-2024
Levtchenko, E. (Recipient), 1 Oct 2009
Prize › Academic