Research output per year
Research output per year
Personal profile
Research interests
- Protease activated receptors and macrophages in pulmonary fibrosis.
- Protease activated receptor 1 in cell fate decesions.
- C/EBPdelta: master regulator of pancreatic cancer progression.
- Mesoporous silica nanoparticles as drug carriers in pancreatic cancer.
Specialisation
Molecular Cell Biology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Identification of C/EBPδ-Modifying Compounds as Potential Anticancer Agents Using a High-Throughput Drug Screen
Hartl, L., Duitman, J., Aberson, H. L., Medema, J. P., Bijlsma, M. F. & Spek, C. A., 1 Feb 2025, In: Journal of cellular and molecular medicine. 29, 3, e70287.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure) -
CAPN2-responsive mesoporous silica nanoparticles: A promising nanocarrier for targeted therapy of pancreatic cancer
Slapak, E. J., el Mandili, M., ten Brink, M. S., Kros, A., Bijlsma, M. F. & Spek, C. A., 28 May 2024, In: Cancer letters. 590, 216845.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Downloads (Pure) -
Hypoxia Abrogates Tumor-Suppressive Activities of C/EBPδ in Pancreatic Cancer
Hartl, L., ten Brink, M. S., Aberson, H. L., Koster, J., Zwijnenburg, D. A., Duitman, J., Bijlsma, M. F. & Spek, C. A., 1 Sept 2024, In: International journal of molecular sciences. 25, 17, 9449.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure) -
Identification of pancreatic cancer-specific protease substrates for protease-dependent targeted delivery
Slapak, E. J., Zwijnenburg, D. A., Koster, J., Bijlsma, M. F. & Spek, C. A., 1 Dec 2024, In: Oncogenesis. 13, 1, 40.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Downloads (Pure) -
C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC
Hartl, L., Roelofs, J. J. T. H., Dijk, F., Bijlsma, M. F., Duitman, J. & Spek, C. A., 1 Jan 2023, In: International journal of molecular sciences. 24, 2, 1537.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure)
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Doctoral committee member Dr Melissa Uil
Spek, C. A. (Examiner)
2022Activity: Examination › Educational
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Cells (Journal)
Spek, C. A. (Member of editorial board)
1 Jan 2021 → …Activity: Publication peer-review and editorial work › Editorial activity
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Biology (Journal)
Spek, C. A. (Member of editorial board)
1 Jan 2020 → …Activity: Publication peer-review and editorial work › Editorial activity