Personal profile
Research interests
Boosting metabolism in T cells; a tool to improve T cell therapy for chronic lymphocytic leukemia patients
Specialisation
Chronic Lymphocytic Leukemia
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Chaja Jacobs is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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When immunity goes rogue: Translational insights into T-cell metabolic and immune dysfunction in CLL
Jacobs, C. F., 2026, 303 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
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Cholesterol homeostasis and lipid raft dynamics at the basis of tumor-induced immune dysfunction in chronic lymphocytic leukemia
Jacobs, C. F., Peters, F. S., Camerini, E., Cretenet, G., Rietveld, J., Schomakers, B. V., van Weeghel, M., Hahn, N., Verberk, S. G. S., van den Bossche, J., Langeveld, M., Kleijwegt, F., Eldering, E., Zelcer, N., Kater, A. P. & Simon-Molas, H., May 2025, In: Cellular & molecular immunology. 22, 5, p. 485-500 16 p., 5932.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile30 Downloads (Pure) -
Daratumumab monotherapy in refractory warm autoimmune hemolytic anemia and cold agglutinin disease
Jalink, M., Jacobs, C. F., Khwaja, J., Evers, D., Bruggeman, C., Fattizzo, B., Michel, M., Crickx, E., Hill, Q. A., Jaeger, U., Kater, A. P., Mäkelburg, A. B. U., Breedijk, A., te Boekhorst, P. A. W., Hoeks, M. P. A., de Haas, M., D’Sa, S. & Vos, J. M. I., 11 Jun 2024, In: Blood. 8, 11, p. 2622-2634 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile39 Downloads (Pure) -
T-cell dysfunction by pseudohypoxia and autocrine purinergic signaling in chronic lymphocytic leukemia
Montironi, C., Jacobs, C. F., Cretenet, G., Peters, F. S., Schomakers, B. V., van Weeghel, M., Kater, A. P., Simon-Molas, H. & Eldering, E., 2023, In: Blood advances. 7, 21, p. 6540-6552 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Kinase inhibitors developed for treatment of hematologic malignancies: Implications for immune modulation in COVID-19
Jacobs, C. F., Eldering, E. & Kater, A. P., 9 Feb 2021, In: Blood advances. 5, 3, p. 913-924 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Downloads (Pure)