Research output per year
Research output per year
Personal profile
Research interests
• Translational studies into cardiac sodium channel (dys)function and inherited sodium channelopathies (including SCN5A mutations) associated with cardiac arrhythmias and sudden cardiac death, incorporating clinical and genetic with functional and mechanistic studies in transgenic models and human induced pluripotent stem cell-derived (iPSC) cardiomyocytes.
• Basic studies aimed at (1) unraveling mechanisms by which defective sodium channels mediate cardiac conduction slowing and arrhythmogenesis, (2) the complexity of sodium channel function and regulation, and (3) their diverse (non-electrogenic) roles in cardiac structure and function.
• Identification of novel (genetic) determinants, modifiers and pathways mediating cardiac electrophysiology and arrhythmia risk.
• Translational studies aimed at identifying novel targets for the prevention and treatment of cardiac arrhythmias and sudden cardiac death.
Specialisation
Basic and translational cardiac electrophysiology
External positions
Chair, Council on Basic Cardiovascular Science, European Society of Cardiology
2026 → 2028
Deputy Editor, Physiological Reviews
Deputy Editor, EP Europace
Associate Editor, Cardiovascular Research
President, Cardiac Electrophysiology Society
Fingerprint
Dive into the research topics where Carol Ann Remme is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 12 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Ventricular hyperinnervation in a mouse model of catecholaminergic polymorphic ventricular tachycardia
O'Reilly, M., Remme, C. A., Casini, S. & de Waal, T. M., 2024, In: Cardiovascular Research.Research output: Contribution to journal › Article › Academic
Open AccessFile -
Targeting the Microtubule EB1-CLASP2 Complex Modulates NaV1.5 at Intercalated Discs
Marchal, G. A., Jouni, M., Chiang, D. Y., Pérez-Hernández, M., Podliesna, S., Yu, N., Casini, S., Potet, F., Veerman, C. C., Klerk, M., Lodder, E. M., Mengarelli, I., Guan, K., Vanoye, C. G., Rothenberg, E., Charpentier, F., Redon, R., George, A. L., Verkerk, A. O. & Bezzina, C. R. & 6 others, , Jul 2021, In: Circulation research. 129, 3, p. 349-365 17 p.Research output: Contribution to journal › Article › Academic › peer-review
-
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility
KORA-Study Group & Nantes Referral Center for inherited cardiac arrhythmia, 1 Mar 2022, In: Nature genetics. 54, 3, p. 232-239 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
A common co-morbiditymodulates disease expression and treatment efficacy in inherited cardiac sodiumchannelopathy
Rivaud, M. R., Jansen, J. A., Postema, P. G., Nannenberg, E. A., Mizusawa, Y., van der Nagel, R., Wolswinkel, R., van der Made, I., Marchal, G. A., Rajamani, S., Belardinelli, L., van Tintelen, J. P., Tanck, M. W. T., van DerWal, A. C., de Bakker, J. M. T., van Rijen, H. V., Creemers, E. E., Wilde, A. A. M., van den Berg, M. P. & van Veen, T. A. B. & 2 others, , 2018, In: European heart journal. 39, 31, p. 2898-2907Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Chronically elevated branched chain amino acid levels are pro-arrhythmic
Portero, V., Nicol, T., Podliesna, S., Marchal, G. A., Baartscheer, A., Casini, S., Tadros, R., Treur, J. L., Tanck, M. W. T., Cox, I. J., Probert, F., Hough, T. A., Falcone, S., Beekman, L., Müller-Nurasyid, M., Kastenmüller, G., Gieger, C., Peters, A., Kääb, S. & Sinner, M. F. & 5 others, , 1 May 2022, In: Cardiovascular research. 118, 7, p. 1742-1757 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile
-
Cardiac Electrophysiological Society, USA (External organisation)
Remme, C. A. (Chair)
2026 → …Activity: Membership › Membership of board › Academic
-
European Heart Rhythm Association (EHRA) (External organisation)
Remme, C. A. (Member)
2026 → …Activity: Membership › Membership of committee › Academic
-
European Society of Cardiology (External organisation)
Remme, C. A. (Chair)
2026 → …Activity: Membership › Membership of board › Academic
-
EP Europace (Journal)
Remme, C. A. (Editor)
2023 → …Activity: Publication peer-review and editorial work › Editorial activity
-
Cardiovascular Research (Journal)
Remme, C. A. (Editor)
2021 → …Activity: Publication peer-review and editorial work › Editorial activity
Prizes
-
-
European Society of Cardiology Silver Medal - William Harvey Basic Science Lecture Award
Remme, C. A. (Recipient), 2025
Prize: Honorary award › Academic
-
Fellow of the European Society of Cardiology (FESC)
Remme, C. A. (Recipient), 2018
Prize: Other distinction
-
Outstanding Achievement Award of the ESC Council of Basic Cardiovascular Science
Remme, C. A. (Recipient), 2018
Prize: Honorary award › Academic
-
Research career highlighted in article “Leaders in Cardiology: Carol Ann Remme”
Remme, C. A. (Recipient), 2026
Prize: Other distinction