Projects per year
Personal profile
Research interests
My main research interest is in the development of new PET tracers to be used in clinical research and drug development and in addition development of radiochemistry needed for these new PET tracers. During my career I have brought >60 PET tracers into clinical research. My research is supported with many grants from EU, IMI, national and international funds in total > 50 M€. I am coordinator of Immune-Image a large European consortium using PET tracers to unveil immune cell dynamics (23 partners, 30 M€, Immune-Image), and I have been work-package leader in 3 EU FP6/7 consortia and 2 MSCA-ITN projects.
I obtained my PhD in radiopharmaceutical chemistry in 1998 with Prof.dr Henk Timmerman, after which I started a post-doc at the lab which I am currently leading, Tracer Center Amsterdam at the Amsterdam UMC Imaging center, part of the department of Radiology and Nuclear Medicine of Amsterdam UMC. In 2002 I was at Uppsala PET center (Sweden) for a sabbatical and in 2014 appointed Professor of radiopharmaceutical chemistry. Tracer Center Amsterdam is regarded by my colleagues as one of the world leading labs for PET tracer development.
recent Grant news: ERC Synergy grant for research on dormant malaria parasites
External positions
Kansen voor West III deskundigen commissie
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Collaborations and top research areas from the last five years
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Projects
- 2 Active
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Unravelling leakage site in patients with Protein Losing Enteropathy
Hurks, R. (Principal investigator), Bouma, G. (Principal investigator), Kramer, G. (Staff), Zwezerijnen, B. (Staff), Soykan, E. (Staff), Eshuis, W. (Staff) & Windhorst, B. (Principal investigator)
01/01/2025 → 31/12/2026
Project: Research
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Synthesis of [18F]aryltriflones for PET imaging
Veth, L. L. (Principal investigator), Vugts, D. (CoPI) & Windhorst, B. (CoPI)
Deutsche Forschungsgemeinschaft
01/01/2023 → …
Project: Research
Research output
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Synthesis and Preclinical Evaluation of [Methylpiperazine-11C]brigatinib as a PET Tracer Targeting Both Mutated Epidermal Growth Factor Receptor and Anaplastic Lymphoma Kinase
Högnäsbacka, A. A., Poot, A. J., Kooijman, E., Schuit, R. C., Schreurs, M., Verlaan, M., Beaino, W., van Dongen, G. A. M. S., Vugts, D. J. & Windhorst, A. D., 14 Sept 2023, In: Journal of medicinal chemistry. 66, 17, p. 12130-12140 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
Development of 18F-Labeled PET Tracer Candidates for Imaging of the Abelson Non-receptor Tyrosine Kinase in Parkinson’s Disease
Stéen, E. J. L., Park, A. Y., Beaino, W., Gadhe, C. G., Kooijman, E., Schuit, R. C., Schreurs, M., Leferink, P., Hoozemans, J. J. M., Kim, J. E., Lee, J. & Windhorst, A. D., 28 Sept 2023, In: Journal of medicinal chemistry. 66, 18, p. 12990-13006 17 p.Research output: Contribution to journal › Article › Academic › peer-review
3 Citations (Scopus) -
State of the art procedures towards reactive [18F]fluoride in PET tracer synthesis
Haveman, L. Y. F., Vugts, D. J. & Windhorst, A. D., 1 Dec 2023, In: EJNMMI Radiopharmacy and Chemistry. 8, 1, 28.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access9 Citations (Scopus) -
Imaging the TGFβ type I receptor in pulmonary arterial hypertension
Rotteveel, L., Poot, A. J., Kooijman, E. J. M., Schuit, R. C., Schalij, I., Sun, X., Kurakula, K., Happé, C., Beaino, W., ten Dijke, P., Lammertsma, A. A., Bogaard, H. J. & Windhorst, A. D., 2023, In: EJNMMI research. 13, 1, 23.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Longitudinal positron emission tomography and postmortem analysis reveals widespread neuroinflammation in SARS-CoV-2 infected rhesus macaques
Nieuwland, J. M., Nutma, E., Philippens, I. H. C. H. M., Böszörményi, K. P., Remarque, E. J., Bakker, J., Meijer, L., Woerdman, N., Fagrouch, Z. C., Verstrepen, B. E., Langermans, J. A. M., Verschoor, E. J., Windhorst, A. D., Bontrop, R. E., de Vries, H. E., Stammes, M. A. & Middeldorp, J., Dec 2023, In: Journal of neuroinflammation. 20, 1, p. 179 1 p., 179.Research output: Contribution to journal › Article › Academic › peer-review
Open Access18 Citations (Scopus)
Prizes
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Fellow of the Society of Radiopharmaceutical Sciences
Windhorst, B. (Recipient), 21 May 2021
Prize: Honorary award › Academic
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