Projects per year
Personal profile
Research interests
Ylstra received a bachelors in Physics in 1988 from the University of Amsterdam (UvA, NL) and commenced with a masters in Genetics at the Vrije Universiteit (VU, NL). In 1995 he received his PhD degree from the same university for work performed at the Universities of Vienna (A) and Nijmegen (NL), Plant Research International (NL) and The John Innes Institute (UK). He was awarded a 2-year NATO fellowship for his post-doctoral work at the University of California in Berkeley (USA) on genome-wide RNA screens . From 1998 he worked at the Comprehensive Cancer Center of the University of California, San Francisco (USA) and was involved in the development of DNA arrays for copy number analysis. In 2001 he accepted his current position at the VU University Medical Center, Cancer Center Amsterdam heading the Tumor Genome Analysis Core. The core has a strong genome laboratory and bioinformatics (pre-)processing track record, with an emphasis on DNA analysis from archival material, see more under http://www.tgac.nl.
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Collaborations and top research areas from the last five years
Projects
- 3 Active
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GEN-BioDORA: A digital GENomics Biobank for Amsterdam Oncology and Neuroscience Research offering secure, reproducible and accessible storage, use and reuse of tissue- and liquid biopsy-derived data.
Ylstra, B. (Principal investigator)
01/09/2024 → 31/08/2029
Project: Research
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SPACETIME 6 van 7 (AMC): SPatial Analysis of Cancer Evolution in the Tumour Immune MicroEnvironment
Ylstra, B. (Principal investigator), Radonic, T. (Project Leader) & Savci Heijink, D. (Project Member)
01/08/2024 → 31/07/2029
Project: Research
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SPACETIME 7 van 7 (AMC): SPatial Analysis of Cancer Evolution in the Tumour Immune MicroEnvironment
Ylstra, B. (Principal investigator) & Kim, Y. (Project Leader)
01/08/2024 → 31/07/2029
Project: Research
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Epstein-Barr virus status drives morphological and molecular intra-tumour heterogeneity in gastric cancer: insights from a case report and literature review
Gullo, I., Sacramento, M. L., Morais, R., Kim, Y., Eijk, P. P., Rocha, A. M., Baptista, D., Santos-Antunes, J., Ylstra, B. & Carneiro, F. T., 2025, (E-pub ahead of print) In: Virchows Archiv.Research output: Contribution to journal › Article › Academic › peer-review
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Integrating genetic subtypes with PET scan monitoring to predict outcome in diffuse large B-cell lymphoma
Mendeville, M. S., Janssen, J., Los-de Vries, G. T., van Dijk, E., Richter, J., Nijland, M., Roemer, M. G. M., Stathi, P., Hijmering, N. J., Bladergroen, R., Pelaz, D. A., Diepstra, A., Eertink, C. J., Burggraaff, C. N., Kim, Y., Lugtenburg, P. J., van den Berg, A., Tzankov, A., Dirnhofer, S. & Dührsen, U. & 5 others, , 1 Dec 2025, In: Nature communications. 16, 1, 109.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Performance and considerations in the use of diagnostic mutation panels for clonality testing in non-small-cell lung carcinoma
Janssen, J., Andrade Barbosa, B., Machado, J. C., Hofman, P., Kim, Y., Ylstra, B. & Radonic, T., 1 May 2025, In: ESMO open. 10, 5, 105072.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
A biopsy-based Immunoscore in patients with treatment-naïve resectable gastric cancer
Soeratram, T. T. D., Beentjes, I., Egthuijsen, J. M. P., Mookhoek, A., Lange, M. M., Meershoek-Klein Kranenbarg, E., Hartgrink, H. H., van de Velde, C. J. H., Ylstra, B., van Laarhoven, H. W. M. & van Grieken, N. C. T., 1 Jan 2024, In: Therapeutic advances in medical oncology. 16Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL
Eken, J. A., Koning, M. T., Kupcova, K., Sepúlveda Yáñez, J. H., de Groen, R. A. L., Quinten, E., Janssen, J., van Bergen, C. A. M., Vermaat, J. S. P., Cleven, A., Navarrete, M. A., Ylstra, B., de Jong, D., Havranek, O., Jumaa, H. & Veelken, H., 6 May 2024, In: Journal of experimental medicine. 221, 5, e20230941.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)