Research output per year
Research output per year
Personal profile
Research interests
My research group strives at understanding cardiac physiology and pathology by combining a wide range of research of approaches including molecular and electrophysiological techniques.
The experiments we perform center around three main research goals:
1. Establishing the molecular and electrophysiological basis of outflow tract arrhythmias.
2.Unraveling the arrhythmogenic mechanisms underlying J-wave syndromes.
3. Development of autonomic nervous system targets for anti-arrhythmic therapy.
4.Characterizing the evolutionary adaptations in cardiac electrophysiology.
Collaborations
Understanding cardiovascular disease requires interdisciplinary research. The combination of genetics, molecular biology and electrophysiology is a powerful method for unravelling disease mechanisms. I often take part in synergic collaborations in the AMC (PMIDs: 32386467, 31666509) and at national (PMID: 32555305, 30681347) and international level (PMIDs: 31695764, 32290757, 27582060).
Specialisation
Developmental, molecular and clinical aspects of life-threatening arrhythmias.
External positions
Associate Professor, Maastricht University: CARIM
… → 1 Feb 2030
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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High-resolution cardiac mapping meets computational imaging to merge structure and function
Boukens, B. J. & Pijnappels, D. A., May 2026, In: Nature cardiovascular research. 5, 5, p. 392-393 2 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
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Functional conduction system mapping in sheep reveals Purkinje spikes in the free wall of the right ventricular outflow tract
Blok, M., den Ouden, B. L., Kuiper, M., Ophelders, D. R. M. G., Jongbloed, M. R. M., Zeemering, S., Jensen, B., van Hunnik, A. & Boukens, B. J., 2025, In: Frontiers in physiology. 16, 1631426.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Hexagonal Multielectrode Design for Recording Local Electrograms With Superior Characteristics
Hoogendijk, M. G., Coronel, R., Arora, R., Kuiper, M., de Groot, N., de Boer, R. A., Vigmond, E. J. & Boukens, B. J., Jul 2025, In: JACC: Clinical Electrophysiology. 11, 7, p. 1606-1612 7 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile -
SCN10A-short gene therapy to restore conduction and protect against malignant cardiac arrhythmias
Wang, J., Verkerk, A. O., Wilders, R., Zhang, Y., Zhang, K., Prakosa, A., Rivaud, M. R., Marsman, E. M. J., Boender, A. R., Klerk, M., Fokkert, L., de Jonge, B., Neef, K., Kirzner, O. F., Bezzina, C. R., Remme, C. A., Tan, H. L., Boukens, B. J., Devalla, H. D. & Trayanova, N. A. & 3 others, , 7 May 2025, In: European heart journal. 46, 18, p. 1747-1762 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
The Brugada syndrome associated gene WT1 impacts on SCN5A expression and cardiac conduction
Marsman, E. M. J., Offerhaus, J., Stervinou, T., Mengarelli, I., Beekman, L., Wilde, L., Casini, S., Streef, T., van den Hoff, M. J. B., Goumans, M. J. T. H., Verkerk, A. O., Jurgens, S. J., Wilde, A. A. M., Lamirault, G., Gaborit, N., Boukens, B. J. D., Remme, C. A., Bezzina, C. & Bosada, F. M., 2025, In: bioRxiv.Research output: Contribution to journal › Article › Academic