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Research interests
The focus of my research project is the improvement of rupture risk prediction and effectiveness of treatment of intracranial aneurysms.
By using 7T MRI, the relation between wall properties (thickness and enhancement) and hemodynamics will be investigated. These images will be acquired in patients with growing and stable aneurysms, in order to:
- identify novel imaging markers that differentiate between aneurysms with different risks of growth or rupture,
- identify new targets for treatment of patients with aneurysms,
- develop and extend clinical prediction models on the growth of intracranial aneurysms and the risk of rupture.
The effectiveness of treatment may be improved by understanding the morphological and hemodynamic changes that the aneurysm will undergo after endovascular treatment. The goal of this project is to improve treatment results by evaluating the effect of:
- hemodynamics on aneurysm recurrence after endovascular treatment,
- stents and flow diverters on aneurysmal hemodynamics.
Specialisation
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Collaborations and top research areas from the last five years
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Augmented Reality Implementation in Minimally Invasive Surgery for Future Application in Pulmonary Surgery: A Systematic Review
Doornbos, M.-C. J., Peek, J. J., Maat, A. P. W. M., Ruurda, J. P., de Backer, P., Cornelissen, B. M. W., Mahtab, E. A. F., Sadeghi, A. H. & Kluin, J., 1 Dec 2024, In: Surgical innovation. 31, 6, p. 646-658 13 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile25 Downloads (Pure) -
Hemodynamic changes after intracranial aneurysm growth
Cornelissen, B. M. W., Leemans, E. L., Slump, C. H., van den Berg, R., Marquering, H. A. & Majoie, C. B. L. M., 1 Jun 2022, In: Journal of neurosurgery. 136, 6, p. 1738-1744 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile38 Downloads (Pure) -
7T versus 3T MR Angiography to Assess Unruptured Intracranial Aneurysms
Leemans, E., Cornelissen, B., Sing, M. L. C., Sprengers, M., van den Berg, R., Roos, Y., Vandertop, W. P., Slump, C., Marquering, H. & Majoie, C., 1 Nov 2020, In: Journal of neuroimaging. 30, 6, p. 779-785 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Downloads (Pure) -
Comparing Morphology and Hemodynamics of Stable-versus-Growing and Grown Intracranial Aneurysms
Leemans, E. L., Cornelissen, B. M. W., Slump, C. H., Majoie, C. B. L. M., Cebral, J. R. & Marquering, H. A., 2019, In: AJNR. American journal of neuroradiology. 40, 12, p. 2102-2110Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Impact of Intracranial Aneurysm Morphology and Rupture Status on the Particle Residence Time
Leemans, E. L., Cornelissen, B. M. W., Rosalini, G., Verbaan, D., Schneiders, J. J., van den Berg, R., Vandertop, W. P., van Bavel, E. T., Slump, C. H., Majoie, C. B. L. M. & Marquering, H. A., 1 Jul 2019, In: Journal of neuroimaging. 29, 4, p. 487-492 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile20 Downloads (Pure)