Personal profile
Research interests
Colorectal Cancer
Specialisation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer
van de Weerd, S., Torang, A., van den Berg, I., Lammers, V., van den Bergh, S., Brouwer, N., Nagtegaal, I. D., Koopman, M., Vink, G. R., van der Baan, F. H., van Krieken, H., Koster, J., Ijzermans, J. N., Roodhart, J. M. L. & Medema, J. P., 15 Jan 2025, In: International Journal of Cancer. 156, 2, p. 456-466 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile20 Downloads (Pure) -
CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
Wouters, V. M., Helderman, R. F. C. P. A., Cameron, K., van der Hooff, S. R., Torang, A., van den Bergh, S., Jackstadt, R., Sansom, O. J., van Neerven, S. M. & Medema, J. P., 7 Jul 2025, In: Oncogene. 44, 25, p. 2091-2102 12 p., 4443.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile22 Downloads (Pure) -
Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability
Torang, A., Kirov, A. B., Lammers, V., Cameron, K., Wouters, V. M., Jackstadt, R. F., Lannagan, T. R. M., de Jong, J. H., Koster, J., Sansom, O. & Medema, J. P., 1 Dec 2025, In: Nature communications. 16, 1, 264.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile29 Downloads (Pure) -
GSK-3 and BCL-XL inhibition mitigates the competitive advantage of APC-mutant colorectal cancer cells
Zhang, L., Atencia Taboada, L., Baglamis, S., de Kroon, M., Elshout, C., Ramesh, P., Helderman, R. F. C. P. A., Torang, A., Cameron, K., van Driel, M. S., Wouters, V. M., van Neerven, S. M. & Medema, J. P., 1 Dec 2025, In: Oncogenesis. 14, 1, 25.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile16 Downloads (Pure) -
Mesenchymal Colorectal Cancers Secrete Vesicles With Unique Cargo That Can Be Used for Liquid Biopsy Based Diagnostics
Asif, P. J., Borghuis, L. H., van Hooff, S. R., Grootemaat, A. E., van Eijndhoven, M. A. J., de Rooij, J., Groenewegen, N. J., Boza, J. P., Kranenburg, O., Rinkes, I. H. M. B., Gómez-Martín, C., Pruijt, H. F. M., van der Wel, N. N., Torang, A., Buffart, T. E., Pegtel, D. M. & Medema, J. P., 1 Nov 2025, In: Journal of extracellular vesicles. 14, 11, e70171.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile23 Downloads (Pure)
Datasets
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Additional file 9 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626332.v1, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626332/1
Dataset
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Additional file 8 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626329.v1, https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626329/1
Dataset
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Additional file 8 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626329, https://springernature.figshare.com/articles/dataset/Additional_file_8_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626329
Dataset
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Additional file 9 of Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, J. Y. (Creator), Gomez Barila, P. M. (Creator), Cameron, K. (Creator), Suijkerbuijk, S. J. E. (Creator), Lieftink, C. (Creator), di Franco, S. (Creator), Krotenberg Garcia, A. (Creator), Uceda Castro, R. (Creator), Lenos, K. J. (Creator), Nijman, L. E. (Creator), Torang, A. (Creator), Longobardi, C. (Creator), de Jong, J. H. (Creator), Dekker, D. (Creator), Stassi, G. (Creator), Vermeulen, L. (Creator), Beijersbergen, R. L. (Creator), van Rheenen, J. (Creator), Huveneers, S. (Creator) & Medema, J. P. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.22626332, https://springernature.figshare.com/articles/dataset/Additional_file_9_of_Subtype-specific_kinase_dependency_regulates_growth_and_metastasis_of_poor-prognosis_mesenchymal_colorectal_cancer/22626332
Dataset