Projects per year
Personal profile
Research interests
Past research of Maitland-van der Zee focused on precision medicine in among others cardiovascular medicine, airway diseases, hematology, oncology, and adverse drug reactions. Her recent research is focused on airways diseases, in particular asthma in children and adults. Precision Medicine refers to the tailoring of medical treatment to the individual characteristics of each patient. It involves the application of “omic” analysis and systems biology to analyze the cause of an individual patient's disease at the molecular level and then to utilize targeted (possibly in combination) to address that individual patient's disease process.
specialisation
Precision Medicine in Respiratory Disease
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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Systems pharmacology approach to difficult-to-treat pediatric asthma (SysPharmPedia)
Maitland-van der Zee, A.-H. (Principal investigator)
01/05/2016 → 09/06/2020
Project: Research
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Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis
Ahmadizar, F., Vijverberg, S. J. H., Arets, H. G. M., de Boer, A., Lang, J. E., Kattan, M., Palmer, C. N. A., Mukhopadhyay, S., Turner, S. & Maitland-van der Zee, A. H., 2016, In: European respiratory journal. 48, 4, p. 1063-1073Research output: Contribution to journal › Article › Academic › peer-review
88 Citations (Scopus) -
A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon
Verhoef, T. I., Ragia, G., de Boer, A., Barallon, R., Kolovou, G., Kolovou, V., Konstantinides, S., le Cessie, S., Maltezos, E., van der Meer, F. J. M., Redekop, W. K., Remkes, M., Rosendaal, F. R., van Schie, R. M. F., Tavridou, A., Tziakas, D., Wadelius, M., Manolopoulos, V. G., Maitland-van der Zee, A. H. & AUTHOR GROUP, 2013, In: New England journal of medicine. 369, 24, p. 2304-2312Research output: Contribution to journal › Article › Academic › peer-review
204 Citations (Scopus) -
Genetic variation in uncontrolled childhood asthma despite ICS treatment
Leusink, M., Vijverberg, S. J. H., Koenderman, L., Raaijmakers, J. A. M., de Jongste, J. C., Sterk, P. J., Duiverman, E. J., Onland-Moret, N. C., Postma, D. S., de Boer, A., de Bakker, P. I. W., Koppelman, G. H. & Maitland-van der Zee, A. H., 2016, In: pharmacogenomics journal. 16, 2, p. 158-163Research output: Contribution to journal › Article › Academic › peer-review
17 Citations (Scopus) -
ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults
Vijverberg, S. J. H., Koster, E. S., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Tse, S. M., Tantisira, K. G., Hawcutt, D. B., Francis, B., Pirmohamed, M., Pino-Yanes, M., Eng, C., Burchard, E. G., Palmer, C. N. A. & Maitland-van der Zee, A. H., 2015, In: Clinical and experimental allergy. 45, 6, p. 1051-1059Research output: Contribution to journal › Article › Academic › peer-review
25 Citations (Scopus) -
Long-term anticoagulant effects of the CYP2C9 and VKORC1 genotypes in acenocoumarol users
Verhoef, T. I., Redekop, W. K., Buikema, M. M., Schalekamp, T., van der Meer, F. J. M., le Cessie, S., Wessels, J. A. M., van Schie, R. M. F., de Boer, A. [., Teichert, M., Visser, L. E., Maitland-van der Zee, A. H. & AUTHOR GROUP, 2012, In: Journal of thrombosis and haemostasis. 10, 4, p. 606-614Research output: Contribution to journal › Article › Academic › peer-review
24 Citations (Scopus)
Datasets
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Additional file 1 of Epigenetic signatures of asthma: a comprehensive study of DNA methylation and clinical markers
Van Asselt, A. J. (Creator), Beck, J. J. (Creator), Finnicum, C. T. (Creator), Johnson, B. N. (Creator), Kallsen, N. (Creator), Viet, S. (Creator), Huizenga, P. (Creator), Ligthart, L. (Creator), Hottenga, J.-J. (Creator), Pool, R. (Creator), der Zee, A. H.M.-V. (Creator), Vijverberg, S. J. (Creator), de Geus, E. (Creator), Boomsma, D. I. (Creator), Ehli, E. A. (Creator) & van Dongen, J. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27569512, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Epigenetic_signatures_of_asthma_a_comprehensive_study_of_DNA_methylation_and_clinical_markers/27569512
Dataset
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Additional file 1: of Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, A. F. (Creator), Holmes, M. V. (Creator), Preiss, D. (Creator), Swerdlow, D. I. (Creator), Denaxas, S. (Creator), Fatemifar, G. (Creator), Faraway, R. (Creator), Finan, C. (Creator), Valentine, D. (Creator), Fairhurst-Hunter, Z. (Creator), Hartwig, F. P. (Creator), Horta, B. L. (Creator), Hypponen, E. (Creator), Power, C. (Creator), Moldovan, M. (Creator), Van Iperen, E. (Contributor), Hovingh, K. (Creator), Demuth, I. (Creator), Norman, K. (Creator), Steinhagen-Thiessen, E. (Creator), Demuth, J. (Creator), Bertram, L. (Creator), Lill, C. M. (Creator), Coassin, S. (Creator), Willeit, J. (Creator), Kiechl, S. (Creator), Willeit, K. (Creator), Mason, D. (Creator), Wright, J. (Creator), Morris, R. (Creator), Wanamethee, G. (Creator), Whincup, P. (Creator), Ben-Shlomo, Y. (Creator), McLachlan, S. (Creator), Price, J. F. (Creator), Kivimaki, M. (Creator), Welch, C. (Creator), Sanchez-Galvez, A. (Creator), Marques-Vidal, P. (Creator), Nicolaides, A. (Creator), Panayiotou, A. G. (Creator), Onland-Moret, N. C. (Creator), Van Der Schouw, Y. T. (Contributor), Matullo, G. (Creator), Fiorito, G. (Creator), Guarrera, S. (Creator), Sacerdote, C. (Creator), Wareham, N. J. (Creator), Langenberg, C. (Creator), Scott, R. A. (Creator), Luan, J. (Creator), Bobak, M. (Creator), Malyutina, S. (Creator), Kubinova, R. (Creator), Tamosiunas, A. (Creator), Pikhart, H. (Creator), Grarup, N. (Creator), Pedersen, O. (Creator), Hansen, T. (Creator), Linneberg, A. (Creator), Jess, T. (Creator), Cooper, J. (Creator), Humphries, S. E. (Creator), Brilliant, M. (Creator), Kitchner, T. (Creator), Hakonarson, H. (Creator), Carrell, D. S. (Creator), McCarty, C. A. (Creator), Lester, K. H. (Creator), Larson, E. B. (Creator), Crosslin, D. R. (Creator), De Andrade, M. (Contributor), Roden, D. M. (Creator), Denny, J. C. (Creator), Carty, C. (Creator), Hancock, S. (Creator), Attia, J. (Creator), Holliday, E. (Creator), Scott, R. (Creator), Schofield, P. (Creator), O'Donnell, M. (Contributor), Yusuf, S. (Creator), Chong, M. (Creator), Pare, G. (Creator), Van Der Harst, P. (Contributor), Said, M. A. (Creator), Eppinga, R. N. (Creator), Verweij, N. (Creator), Snieder, H. (Creator), Christen, T. (Creator), Mook-Kanamori, D. O. (Creator), Gustafsson, S. (Creator), Lind, L. (Creator), Ingelsson, E. (Creator), Pazoki, R. (Creator), Franco, O. (Creator), Hofman, A. (Creator), Uitterlinden, A. (Creator), Dehghan, A. (Creator), Teumer, A. (Creator), Baumeister, S. (Creator), Dörr, M. (Contributor), Lerch, M. M. (Creator), Völker, U. (Contributor), Völzke, H. (Contributor), Ward, J. (Creator), Pell, J. P. (Creator), Meade, T. (Creator), Christophersen, I. E. (Creator), Maitland-Van Der Zee, A. H. (Contributor), Baranova, E. V. (Creator), Young, R. (Creator), Ford, I. (Creator), Campbell, A. (Creator), Padmanabhan, S. (Creator), Bots, M. L. (Creator), Grobbee, D. E. (Creator), Froguel, P. (Creator), Thuillier, D. (Creator), Roussel, R. (Creator), Bonnefond, A. (Creator), Cariou, B. (Creator), Smart, M. (Creator), Bao, Y. (Creator), Kumari, M. (Creator), Mahajan, A. (Creator), Hopewell, J. C. (Creator), Seshadri, S. (Creator), Dale, C. (Creator), Costa, R. P. E. (Creator), Ridker, P. M. (Creator), Chasman, D. I. (Creator), Reiner, A. P. (Creator), Ritchie, M. D. (Creator), Lange, L. A. (Creator), Cornish, A. J. (Creator), Dobbins, S. E. (Creator), Hemminki, K. (Creator), Kinnersley, B. (Creator), Sanson, M. (Creator), Labreche, K. (Creator), Simon, M. (Creator), Bondy, M. (Creator), Law, P. (Creator), Speedy, H. (Creator), Allan, J. (Creator), Li, N. (Creator), Went, M. (Creator), Weinhold, N. (Creator), Morgan, G. (Creator), Sonneveld, P. (Creator), Nilsson, B. (Creator), Goldschmidt, H. (Creator), Sud, A. (Creator), Engert, A. (Creator), Hansson, M. (Creator), Hemingway, H. (Creator), Asselbergs, F. W. (Creator), Patel, R. S. (Creator), Keating, B. J. (Creator), Sattar, N. (Creator), Houlston, R. (Creator), Casas, J. P. (Creator) & Hingorani, A. D. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10086278.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Phenome-wide_association_analysis_of_LDL-cholesterol_lowering_genetic_variants_in_PCSK9/10086278/1
Dataset
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Additional file 1: of Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, A. F. (Creator), Holmes, M. V. (Creator), Preiss, D. (Creator), Swerdlow, D. I. (Creator), Denaxas, S. (Creator), Fatemifar, G. (Creator), Faraway, R. (Creator), Finan, C. (Creator), Valentine, D. (Creator), Fairhurst-Hunter, Z. (Creator), Hartwig, F. P. (Creator), Horta, B. L. (Creator), Hypponen, E. (Creator), Power, C. (Creator), Moldovan, M. (Creator), Van Iperen, E. (Contributor), Hovingh, K. (Creator), Demuth, I. (Creator), Norman, K. (Creator), Steinhagen-Thiessen, E. (Creator), Demuth, J. (Creator), Bertram, L. (Creator), Lill, C. M. (Creator), Coassin, S. (Creator), Willeit, J. (Creator), Kiechl, S. (Creator), Willeit, K. (Creator), Mason, D. (Creator), Wright, J. (Creator), Morris, R. (Creator), Wanamethee, G. (Creator), Whincup, P. (Creator), Ben-Shlomo, Y. (Creator), McLachlan, S. (Creator), Price, J. F. (Creator), Kivimaki, M. (Creator), Welch, C. (Creator), Sanchez-Galvez, A. (Creator), Marques-Vidal, P. (Creator), Nicolaides, A. (Creator), Panayiotou, A. G. (Creator), Onland-Moret, N. C. (Creator), Van Der Schouw, Y. T. (Contributor), Matullo, G. (Creator), Fiorito, G. (Creator), Guarrera, S. (Creator), Sacerdote, C. (Creator), Wareham, N. J. (Creator), Langenberg, C. (Creator), Scott, R. A. (Creator), Luan, J. (Creator), Bobak, M. (Creator), Malyutina, S. (Creator), Kubinova, R. (Creator), Tamosiunas, A. (Creator), Pikhart, H. (Creator), Grarup, N. (Creator), Pedersen, O. (Creator), Hansen, T. (Creator), Linneberg, A. (Creator), Jess, T. (Creator), Cooper, J. (Creator), Humphries, S. E. (Creator), Brilliant, M. (Creator), Kitchner, T. (Creator), Hakonarson, H. (Creator), Carrell, D. S. (Creator), McCarty, C. A. (Creator), Lester, K. H. (Creator), Larson, E. B. (Creator), Crosslin, D. R. (Creator), De Andrade, M. (Contributor), Roden, D. M. (Creator), Denny, J. C. (Creator), Carty, C. (Creator), Hancock, S. (Creator), Attia, J. (Creator), Holliday, E. (Creator), Scott, R. (Creator), Schofield, P. (Creator), O'Donnell, M. (Contributor), Yusuf, S. (Creator), Chong, M. (Creator), Pare, G. (Creator), Van Der Harst, P. (Contributor), Said, M. A. (Creator), Eppinga, R. N. (Creator), Verweij, N. (Creator), Snieder, H. (Creator), Christen, T. (Creator), Mook-Kanamori, D. O. (Creator), Gustafsson, S. (Creator), Lind, L. (Creator), Ingelsson, E. (Creator), Pazoki, R. (Creator), Franco, O. (Creator), Hofman, A. (Creator), Uitterlinden, A. (Creator), Dehghan, A. (Creator), Teumer, A. (Creator), Baumeister, S. (Creator), Dörr, M. (Contributor), Lerch, M. M. (Creator), Völker, U. (Contributor), Völzke, H. (Contributor), Ward, J. (Creator), Pell, J. P. (Creator), Meade, T. (Creator), Christophersen, I. E. (Creator), Maitland-Van Der Zee, A. H. (Contributor), Baranova, E. V. (Creator), Young, R. (Creator), Ford, I. (Creator), Campbell, A. (Creator), Padmanabhan, S. (Creator), Bots, M. L. (Creator), Grobbee, D. E. (Creator), Froguel, P. (Creator), Thuillier, D. (Creator), Roussel, R. (Creator), Bonnefond, A. (Creator), Cariou, B. (Creator), Smart, M. (Creator), Bao, Y. (Creator), Kumari, M. (Creator), Mahajan, A. (Creator), Hopewell, J. C. (Creator), Seshadri, S. (Creator), Dale, C. (Creator), Costa, R. P. E. (Creator), Ridker, P. M. (Creator), Chasman, D. I. (Creator), Reiner, A. P. (Creator), Ritchie, M. D. (Creator), Lange, L. A. (Creator), Cornish, A. J. (Creator), Dobbins, S. E. (Creator), Hemminki, K. (Creator), Kinnersley, B. (Creator), Sanson, M. (Creator), Labreche, K. (Creator), Simon, M. (Creator), Bondy, M. (Creator), Law, P. (Creator), Speedy, H. (Creator), Allan, J. (Creator), Li, N. (Creator), Went, M. (Creator), Weinhold, N. (Creator), Morgan, G. (Creator), Sonneveld, P. (Creator), Nilsson, B. (Creator), Goldschmidt, H. (Creator), Sud, A. (Creator), Engert, A. (Creator), Hansson, M. (Creator), Hemingway, H. (Creator), Asselbergs, F. W. (Creator), Patel, R. S. (Creator), Keating, B. J. (Creator), Sattar, N. (Creator), Houlston, R. (Creator), Casas, J. P. (Creator) & Hingorani, A. D. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10086278, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Phenome-wide_association_analysis_of_LDL-cholesterol_lowering_genetic_variants_in_PCSK9/10086278
Dataset
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Additional file 1 of Epigenetic signatures of asthma: a comprehensive study of DNA methylation and clinical markers
Van Asselt, A. J. (Creator), Beck, J. J. (Creator), Finnicum, C. T. (Creator), Johnson, B. N. (Creator), Kallsen, N. (Creator), Viet, S. (Creator), Huizenga, P. (Creator), Ligthart, L. (Creator), Hottenga, J.-J. (Creator), Pool, R. (Creator), der Zee, A. H.M.-V. (Creator), Vijverberg, S. J. (Creator), de Geus, E. (Creator), Boomsma, D. I. (Creator), Ehli, E. A. (Creator) & van Dongen, J. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27569512.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Epigenetic_signatures_of_asthma_a_comprehensive_study_of_DNA_methylation_and_clinical_markers/27569512/1
Dataset
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Additional file 2 of Epigenetic signatures of asthma: a comprehensive study of DNA methylation and clinical markers
Van Asselt, A. J. (Creator), Beck, J. J. (Creator), Finnicum, C. T. (Creator), Johnson, B. N. (Creator), Kallsen, N. (Creator), Viet, S. (Creator), Huizenga, P. (Creator), Ligthart, L. (Creator), Hottenga, J.-J. (Creator), Pool, R. (Creator), der Zee, A. H.M.-V. (Creator), Vijverberg, S. J. (Creator), de Geus, E. (Creator), Boomsma, D. I. (Creator), Ehli, E. A. (Creator) & van Dongen, J. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.27569515.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Epigenetic_signatures_of_asthma_a_comprehensive_study_of_DNA_methylation_and_clinical_markers/27569515/1
Dataset