Research output per year
Research output per year
Personal profile
Specialisation
Associate Professor of Youth Affective Disorders: Improving Outcomes through the Exposome and Art-Science Integration.
#Mental Health, Affective Disorders, Biological Psychiatry, Metabolic Psychiatry, Psychonomics, Mood disorders. Youth and neuromodulation, Gut-brain-axis.
#Art: Conceptual art, Installation Art, Improvisation art. Immersive experience. Biobased art. Art based learning. Neuroaesthetics.
Research interests
My work as psychiatrist and principal investigator conceptualizes affective disorders in adolescents and young adults as exposome-shaped conditions arising from dynamic interactions between neurodevelopment, immune–metabolic and microbiome systems, and social–environmental stressors. I integrate transitional psychiatry, systems neuroscience, and population-based epidemiology with mechanistic and art–science–based translational research, focusing on anhedonia and affective dysregulation during critical developmental transitions. As founder and lead of the Transitiecentrum Affectieve Stoornissen (TAS) and PI of MoodLabMeets, I develop exposome-informed, developmentally grounded psychobiological interventions that link biological mechanisms, embodied experience, and environmental context.
Education/Academic qualification
Basiskwalificatie Onderwijs (BKO), Amsterdam UMC
Award Date: 18 Apr 2019
External positions
Associate PI, UvA, The Centre for Urban Mental Health, UvA, Amsterdam
Keywords
- QR180 Immunology
- R Medicine (General)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 10 Reduced Inequalities
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A 3-Month Follow-Up Pilot Study on Accelerated Intermittent Theta Burst Stimulation for Bipolar Depression
Neuteboom, D., Pahladsingh, U., Steinbach, M. C., Ploegaert, M. C., Zantvoord, J. B., Lok, A., de Haan, L. & Scheepstra, K. W. F., 1 Aug 2026, In: Bipolar disorders. 28, 5, e70148.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Alterations in lipid, redox, and energy metabolism in recent onset psychosis: a metabolomics study in non-smoking individuals and matched controls
Dielemans, D. A. M., Sutterland, A. L., Lutter, R., van Weeghel, M., Bourgonje, A. R., Tan, H. L., van Goor, H., Lok, A., van Beveren, N. J. M., de Haan, L. & Hagen, J. M., 1 Feb 2026, In: Redox Biology. 89, 103999.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile56 Downloads (Pure) -
Effectiveness of electroconvulsive therapy for depression: comparing research studies with real-world clinical data from the Dutch ECT consortium
Cobben, R. C., Loef, D., van Dellen, E., Hagoort, K., van de Ven, P. M., Schut, B., Lok, A., Mocking, R. J. T., Scheepstra, K. W. F., van Exel, E., Oudega, M. L., Broekman, B. F. P., Vergouwen, A. C. M., Zoon, T. J. C., Kok, R. M., Angevaare, M., Verwijk, E., Rovers, J. J. E., Tendolkar, I. & Pottkämper, J. C. M. & 18 others, , 1 Jun 2026, In: Comprehensive psychiatry. 148, 152723.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
From gut to glee: Is butyrate a promising antidepressant? A systematic review and mechanistic insights
Korenblik, V., Schilder, N. K. M., de Lange, I. G. S., Daams, J. G., Bockting, C. L. H., Brul, S., Nieuwdorp, M., Lok, A. & Korosi, A., 1 Feb 2026, In: Brain, behavior, and immunity. 132, 106237.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile26 Downloads (Pure) -
Neurobiological mechanisms of anhedonia in adolescents with mood disorders: A scoping review
Lok, A., Kemble, A. N., Mol, F., Hoxha, H. & Bergfeld, I. O., 15 Jun 2026, In: Journal of affective disorders. 403, 121376.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile19 Downloads (Pure)
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Nederlands Veteranen Instituut (External organisation)
Lok, A. (Member)
1 Jun 2024 → 1 Jun 2028Activity: Membership › Membership of committee › Academic
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Relationship Between the Microbiome and Posttraumatic Stress Disorder: A Scope on Pre-Clinical and Human (intervention) Studies
Lok, A. (Speaker)
10 May 2024Activity: Talk or presentation › Oral presentation › Academic
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Mood Disorders in Youth: focus on anhedonia
Lok, A. (Speaker)
7 May 2024Activity: Talk or presentation › Invited talk › Academic
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Mental Health in migrants: An urban perspective
Lok, A. (Speaker)
11 Apr 2024Activity: Talk or presentation › Invited talk › Professional
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De Nederlandstalige Vereniging voor Psychotrauma (NtVP) (External organisation)
Lok, A. (Member)
2 Jan 2024 → 29 Feb 2024Activity: Membership › Membership of committee › Academic
Prizes
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First recipient of the European Certificate Psychotraumatology
Lok, A. (Recipient), 4 Jan 2009
Prize: Other distinction
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Make sense: sensitized brain circuits for rTMS-induced neuroplasticity
Lok, A. (Recipient), 5 Jul 2021
Prize › Academic
Press/Media
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Rijksmuseum Boerhaave Leiden. Tentoonstelling 2023-2024: Onvoorstelbaar
18/04/2023
1 Media contribution
Press/Media: Press / Media
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Het Parool: Groot Amsterdams onderzoek: etnische achtergrond speelt rol bij depressies, diabetes, hartkwalen
07/03/2023
1 Media contribution
Press/Media: Press / Media
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Janus: Het gedeprimeerde brein weer in balans brengen
01/03/2023
1 Media contribution
Press/Media: Press / Media
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Trouw: Bacteriën in de darmen beïnvloeden depressie, blijkt na dertig jaar onderzoek
10/12/2022
1 Media contribution
Press/Media: Press / Media
Courses
Datasets
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The relationship between the microbiome and posttraumatic stress disorder: a protocol for a scoping review
Berendse, R. (Contributor), Zantvoord, J. B. (contactPerson), Lindauer, R. J. L. (Contributor), Daams, J. G. (Contributor), Korosi, A. (Contributor), Hemmings, S. M. J. (Contributor) & Lok, A. (Contributor), DataverseNL, 13 Mar 2024
DOI: 10.34894/H4Y9QS, https://doi.org/10.34894/H4Y9QS
Dataset