Projects per year
Personal profile
Research interests
Thyroid hormone metabolism in innate immune cells
Central and peripheral thyroid hormone metabolism during inflammation
Hypothalamus-pituitary-thyroid axis
Congenital hypothyroidism
Specialisation
thyroid hormone metabolism, neonatal screening
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Collaborations and top research areas from the last five years
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The Gut2gd study: The GUT2GD study: do changes in the gut microbiome trigger Graves’ Disease?
Boelen, A. (Principal investigator) & van der Spek, A. (Project Leader)
Stichting Amsterdams Universiteitsfonds
01/11/2024 → 30/09/2025
Project: Research
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TH-NAFLD: Thyroid hormone titration for subclinical hypothyroidism in NAFLD patients
Boelen, A. (Principal investigator)
ETA European Thyroid Association
01/07/2022 → 31/12/2025
Project: Research
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RUBICON: The role of thyroid hormone in the development of hepatic insulin resistance
Boelen, A. (Principal investigator)
01/02/2021 → 30/04/2022
Project: Research
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Resistance to Thyroid Hormone Alpha: Macrophage differentiation and function in patients with Resistance to Thyroid Hormone Alpha
Boelen, A. (Principal investigator)
European Society of Endocrinology
10/02/2020 → 31/12/2021
Project: Research
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CEFIC: LRI-EMSG59: Developing a quantitative AOP for liver-mediated thyroid modulation after prenatal exposure to a xenobiotic compound in the rat
Boelen, A. (Principal investigator)
RIVM: Rijksinstituut voor Volksgezondheid en Milieu
01/03/2019 → 31/12/2021
Project: Research
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The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils
van der Spek, A. H., Bloise, F. F., Tigchelaar, W., Dentice, M., Salvatore, D., van der Wel, N. N., Fliers, E. & Boelen, A., 2016, In: Endocrinology. 157, 8, p. 3293-3305Research output: Contribution to journal › Article › Academic › peer-review
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Mutations in TBL1X Are Associated With Central Hypothyroidism
Heinen, C. A., Losekoot, M., Sun, Y., Watson, P. J., Fairall, L., Joustra, S. D., Zwaveling-Soonawala, N., Oostdijk, W., van den Akker, E. L. T., Alders, M., Santen, G. W. E., van Rijn, R. R., Dreschler, W. A., Surovtseva, O. V., Biermasz, N. R., Hennekam, R. C., Wit, J. M., Schwabe, J. W. R., Boelen, A. & Fliers, E. & 1 others, , 2016, In: Journal of clinical endocrinology and metabolism. 101, 12, p. 4564-4573Research output: Contribution to journal › Article › Academic › peer-review
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A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages
Kwakkel, J., Surovtseva, O. V., de Vries, E. M., Stap, J., Fliers, E. & Boelen, A., 2014, In: Endocrinology. 155, 7, p. 2725-2734Research output: Contribution to journal › Article › Academic › peer-review
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Evaluation of the Performance of Newborn Screening for Tyrosinemia Type 1 in The Netherlands: Suggestions for Improvements Using Additional Biomarkers in Addition to Succinylacetone
Bouva, M. J., Kuypers, A. M., Kemper, E. A., Maase, R. E., Bosch, A. M., van Spronsen, F. J., Heijboer, A. C., Heiner-Fokkema, M. R., Heil, S. G. & Boelen, A., 1 Jun 2025, In: International journal of neonatal screening. 11, 2, 35.Research output: Contribution to journal › Article › Academic › peer-review
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Leeftijdsspecifieke referentie-intervallen voor TSH en schildklierhormoon‡
den Elzen, W. P. J., Jansen, H. I., Dirks, N. F., Hillebrand, J. J., van Trotsenburg, A. S. P., den Heijer, M., Bruinstroop, E., Boelen, A. & Heijboer, A. C., 9 Apr 2025, In: Nederlands tijdschrift voor geneeskunde. 9Translated title of the contribution :Age-specific reference intervals for thyroid-stimulating hormone and free thyroxine to optimize diagnosis of thyroid disease Research output: Contribution to journal › Article › Professional
Datasets
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Supplementary Material for: Improving the Dutch Newborn Screening for Central Congenital Hypothyroidism by Using 95% Reference Intervals for Thyroxine-Binding Globulin
Stroek, K. (Creator), Heijboer, A. C. (Creator), Bosch, A. M. (Creator), Zwaveling-Soonawala, N. (Creator) & Boelen, A. (Creator), Karger Publishers, 2021
DOI: 10.6084/m9.figshare.14169713, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Improving_the_Dutch_Newborn_Screening_for_Central_Congenital_Hypothyroidism_by_Using_95_Reference_Intervals_for_Thyroxine-Binding_Globulin/14169713
Dataset
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Supplementary Material for: Improving the Dutch Newborn Screening for Central Congenital Hypothyroidism by Using 95% Reference Intervals for Thyroxine-Binding Globulin
Stroek, K. (Creator), Heijboer, A. C. (Creator), Bosch, A. M. (Creator), Zwaveling-Soonawala, N. (Creator) & Boelen, A. (Creator), Karger Publishers, 2021
DOI: 10.6084/m9.figshare.14169713.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Improving_the_Dutch_Newborn_Screening_for_Central_Congenital_Hypothyroidism_by_Using_95_Reference_Intervals_for_Thyroxine-Binding_Globulin/14169713/1
Dataset