Research output per year
Research output per year
Personal profile
Research interests
My research interests focus on the role oxidative stress in critically ill patients. I investigated the effects of hyperoxemia (translational research investigating the cardiovascular effects of hyperoxia and optimal oxygenation in critically ill patients ). Furthermore, my research revolves around micronutrients (particularly vitamin C) in the critically ill patients. Besides studying the effects of vitamin C in post-cardiac arrest patients, we search for new analytical methods to reliably estimate micronutrient body status to faciliate predictive enrichment of new clinical trials and to personalize micronutrient therapy in critically ill patients. Furthermore, new treatments of hemato-oncological ICU-patients (CAR-T and bispecific antibodies) will be a new field of research .
Education/Academic qualification
PhD, Clinical studies on new cardiovascular risk determinants in type 2 diabetes mellitus.
Award Date: 28 Jun 2006
Keywords
- RZ Other systems of medicine
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Collaborations and top research areas from the last five years
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Early high-dose vitamin C for out-of-hospital cardiac arrest: the VITaCCA randomized clinical trial
Rozemeijer, S., Dubois, E. A., de Grooth, H.-J., den Uil, C. A., Rettig, T. C. D., Rijpstra, T. A., van den Bogaard, B., van Zanten, A. R. H., Bosman, R. J., Elbers, P. W. G., Girbes, A. R. J., Vlaar, A. P. J., Twisk, J. W. R., Christopher, K. B., Schober, P., Oudemans-van Straaten, H. M. & de Man, A. M. E., 1 Jul 2026, In: Intensive care medicine. 52, 7, p. 1447-1457 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Treatment of catheter related thrombosis: A systematic review, meta-analysis, and national survey
Oomen, L. A., van Diest, J., Lucas, F. R. M., Rijpkema, J., Burchell, G. L., van Zanten, F. J. L., Choi, K. F., Muller, M. C. A., de Man, A. M. E., Vlaar, A. P. J., Heijmans, J., Biemond, B. J., van Es, N., Smit, J. M. & Tuinman, P. R., Mar 2026, In: Journal of Vascular Surgery: Venous and Lymphatic Disorders. 14, 2, p. 102359 102359.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile2 Downloads (Pure) -
Corrigendum to "ESPEN practical short micronutrient guideline" [Clin Nutr 43 (2024) 825-857]
Berger, M. M., Shenkin, A., Dizdar, O. S., Amrein, K., Augsburger, M., Biesalski, H.-K., Bischoff, S. C., Casaer, M. P., Gundogan, K., Lepp, H.-L., de Man, A. M. E., Muscogiuri, G., Pietka, M., Pironi, L., Rezzi, S., Schweinlin, A. & Cuerda, C., Jul 2025, In: Clinical nutrition (Edinburgh, Scotland). 50, p. 75Research output: Contribution to journal › Article › Academic › peer-review
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Corrigendum to "LLL 44-1 micronutrients in clinical nutrition: Trace elements" [Clin Nutr ESPEN 61 (2024) 369-376]
ESPEN Micronutrient Special Interest Group (SIG-MN), Jun 2025, In: Clinical nutrition ESPEN. 67, p. 700Research output: Contribution to journal › Article › Academic › peer-review
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Corrigendum to "LLL 44 - 2 micronutrients in clinical nutrition: Vitamins" [Clin Nutr ESPEN 61 (2024) 427-436]
ESPEN Micronutrient Special Interest Group (SIG-MN), Jun 2025, In: Clinical nutrition ESPEN. 67, p. 701Research output: Contribution to journal › Article › Academic › peer-review
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REMAP-CAP symposium: vitamin C in COVID-19
Spoelstra-de Man, A. (Speaker)
8 Dec 2022Activity: Talk or presentation › Oral presentation › Academic
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ESPEN: The Science of Micronutrients in Clinical Nutrition Vitamins in sepsis
Spoelstra-de Man, A. (Speaker)
8 Nov 2022Activity: Talk or presentation › Oral presentation › Academic
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ESICM: Micronutrients in the ICU, the clinical evidence | Monitoring and tailoring micronutrients to specific ICU patients
Spoelstra-de Man, A. (Speaker)
22 Oct 2022Activity: Talk or presentation › Oral presentation › Academic
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Mythen, Missers en Maatwerk Respiratoire Insufficiëntie en Beademing: We geven te veel zuurstof op de IC
Spoelstra-de Man, A. (Speaker)
28 Sept 2022Activity: Talk or presentation › Oral presentation › Academic