Personal profile
Research interests
Lead scientist in fundamental and translational immunology with an extensive experience in cancer and autoimmunity research. My research focuses on developing novel therapeutic nanovaccines, by harnessing dendritic cells to drive anti-cancer immune responses or to dampen in autoimmune diseases.
Specialisation
Immunology / Dendritic cells / Cancer / Autoimmunity
Related documents
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Comparing DC subsets in solid tumors: what about DC3s?
Pachocki, C. J., Boes, M. & Affandi, A. J., 2025, In: Immunotherapy Advances. 5, 1, ltaf021.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile13 Downloads (Pure) -
Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes
Wang, A. Z., Brink, H. J., Bouma, R. G., Affandi, A. J., Nijen Twilhaar, M. K., Heijnen, D. A. M., van Elk, J., Maaskant, J. J., Konijn, V. A. L., Stolwijk, J. G. C., Kalay, H., Olesek, K., van Kooyk, Y., van der Schoot, J. M. S., Bentlage, A. E. H., Scheeren, F. A., Verdoes, M., Vidarsson, G., Kuijl, C. P. & den Haan, J. M. M., 20 Nov 2024, In: Bioconjugate chemistry. 35, 11, p. 1805-1814 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Downloads (Pure) -
Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis
Carvalheiro, T., Marut, W., Pascoal Ramos, M. I., García, S., Fleury, D., Affandi, A. J., Meijers, A. S., Giovannone, B., Tieland, R. G., Elshof, E., Ottria, A., Cossu, M., Meizlish, M. L., Veenendaal, T., Ramanujam, M., Moreno-García, M. E., Klumperman, J., Liv, N., Radstake, T. R. D. J. & Meyaard, L., 1 Jun 2024, In: Journal of autoimmunity. 146, 103219.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile19 Downloads (Pure) -
In-depth immune profiling of peripheral blood mononuclear cells in patients with pancreatic ductal adenocarcinoma reveals discriminative immune subpopulations
Rodriguez, E., Zwart, E. S., Affandi, A. A., Verhoeff, J., de Kok, M., Boyd, L. N. C., Meijer, L. L., le Large, T. Y. S., Olesek, K., Giovannetti, E., García-Vallejo, J. J., Mebius, R. E., van Kooyk, Y. & Kazemier, G., Jul 2024, In: Cancer science. 115, 7, p. 2170-2183 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile22 Downloads (Pure) -
Nanobody-liposomes as novel cancer vaccine platform to efficiently stimulate T cell immunity
Bouma, R. G., Nijen Twilhaar, M. K., Brink, H. J., Affandi, A. J., Mesquita, B. S., Olesek, K., van Dommelen, J. M. A., Heukers, R., de Haas, A. M., Kalay, H., Ambrosini, M., Metselaar, J. M., van Rooijen, A., Storm, G., Oliveira, S., van Kooyk, Y. & den Haan, J. M. M., 20 Jul 2024, In: International journal of pharmaceutics. 660, 124254.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Downloads (Pure)
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NWO Life Sciences with Industry 2024
Affandi, A. (Participant)
13 May 2024 → 17 May 2024Activity: Participating in or organising an event › participating
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NVVI Spring Meeting 2024
Affandi, A. (Participant)
22 Mar 2024Activity: Participating in or organising an event › participating
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CD169-directed nanovaccines and immunophenotying of blood dendritic cells in melanoma
Affandi, A. (Speaker)
29 Feb 2024Activity: Talk or presentation › Invited talk › Academic
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European Macrophage and Dendritic Cell Society
Affandi, A. (Participant)
18 Oct 2023 → 20 Oct 2023Activity: Participating in or organising an event › participating
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Single-Domain Antibodies 2023
Affandi, A. (Participant)
18 Sept 2023 → 20 Sept 2023Activity: Participating in or organising an event › participating
Prizes
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Cancer Center Amsterdam Pre-clinical publication award
Affandi, A. (Recipient), 17 Jun 2021
Prize › Academic
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