Research output per year
Research output per year
Personal profile
Research interests
- Cellular innate immune responses against bacteria during pneumosepsis
- Btk-depedent effector functions of myeloid cells against bacteria
- Epigenetic regulation of monocyte reprogramming during sepsis
Specialisation
Biology - Immunology
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Dive into the research topics where Alexander de Vos is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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mTOR inhibition impacts the flagellin-augmented inflammatory and antimicrobial response of human airway epithelial cells to Pseudomonas aeruginosa
van Linge, C. C. A., Hulme, K. D., Peters-Sengers, H., Kullberg, R. F. J., de Jong, M. D., Russell, C. A., de Vos, A. F. & van der Poll, T., 1 May 2025, In: PLoS ONE. 20, 5 May, e0321462.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Role of Liver Kinase 1B in Platelet Activation and Host Defense During Klebsiella pneumoniae-Induced Pneumosepsis
Chouchane, O., Léopold, V., van Linge, C. C. A., de Vos, A. F., Roelofs, J. J. T. H., van ‘t Veer, C. & van der Poll, T., 1 Apr 2025, In: International journal of molecular sciences. 26, 8, 3714.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Immunostimulatory Effect of Flagellin on MDR-Klebsiella-Infected Human Airway Epithelial Cells
van Linge, C. C. A., Hulme, K. D., Peters-Sengers, H., Sirard, J.-C., Goessens, W. H. F., de Jong, M. D., Russell, C. A., de Vos, A. F. & van der Poll, T., 1 Jan 2024, In: International journal of molecular sciences. 25, 1, 309.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus) -
Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome
Michels, E. H. A., Chouchane, O., de Brabander, J., de Vos, A. F., Faber, D. R., Douma, R. A., Smit, E. R., Wiersinga, W. J., van den Biggelaar, M., van der Poll, T. & Hoogendijk, A. J., 2024, In: Frontiers in immunology. 15, p. 1470383 1470383.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin
Ramirez-Moral, I., Schuurman, A. R., van Linge, C. C. A., Butler, J. M., Yu, X., de Haan, K., van Leeuwen, S., de Vos, A. F., de Jong, M. D., Vieira Braga, F. A. & van der Poll, T., 20 Sept 2024, In: iScience. 27, 9, 110662.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus)