Research output per year
Research output per year
Personal profile
Research interests
With a strong background in renal aging and diseases, I study the metabolic changes and the impact of environmental toxins in these conditions.
My recent work focuses on understanding the biological mechanisms of premature renal aging, particularly the role of senescent kidney epithelial cells. The accumulation of these cells is a critical risk factor for the progression of chronic kidney disease. I investigate NAD+ metabolism, complex lipid metabolism, and immunometabolism in senescent cells during aging and disease to discover new therapeutic strategies for healthy renal aging and to slow chronic kidney disease progression.
Additionally, I study how fine and ultrafine particles from air pollution contribute to premature renal aging from early life onwards.
My research utilizes patient-derived kidney tissue, animal models, in vitro models of senescence, senescence assays, metabolic assays, iPSCs-derived kidney organoids, exposome chambers, various omics techniques, and histology.
Specialisation
kidney disease, aging, senescence, metabolism, air pollution, exposome studies, developmental programming
Related documents
External positions
visiting scientist, University of São Paulo Medical School
Keywords
- RJ101 Child Health. Child health services
- RB Pathology
- RM Therapeutics. Pharmacology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy -
SDG 10 Reduced Inequalities -
SDG 12 Responsible Consumption and Production -
SDG 13 Climate Action
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Collaborations and top research areas from the last five years
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Research output
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Global environmental change and the gut-kidney-brain axis: a review and framework of vulnerability and resilience
Climate-Kidneys-Cognition Working Group, Apr 2026, In: The Lancet Planetary Health. 10, 4, p. 101453 101453.Research output: Contribution to journal › Review article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
Kidney morphological changes associated with early-life carbonaceous ultrafine particle exposure: A pathomics approach
Rasking, L., Vanbrabant, K., Sun, P., Vangeneugden, M., Strauch, M., Schins, R. P. F., Cassee, F. R., Bové, H., de Vusser, K., Nawrot, T. S., Tammaro, A., Boor, P. & Plusquin, M., 15 Nov 2025, In: Environmental research. 285, 122458.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile38 Downloads (Pure) -
Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells
Marin-Blazquez, M., Tammaro, A., Rabadan-Ros, R. & Zapata-Perez, R., 21 Nov 2025, In: Journal of visualized experiments. 2025-November, 225, p. 1-15 15 p., e69077.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Downloads (Pure) -
NNMT promotes tubular senescence and fibrosis in chronic kidney disease
Chanvillard, L., Lantermans, H., Wall, C., Thevenet, J., Butter, L., Tauzin, L., Claessen, N., Christen, S., Karaz, S., Lassueur, S., Lizzo, G., Sanchez-Garcia, J. L., Métairon, S., Holzwarth, J. A., Ferro, V., Moco, S., van Bommel, E. J. M., van Baar, M. J. B., Hesp, A. C. & van Raalte, D. H. & 5 others, , 1 Jan 2025, In: bioRxiv. p. 2025.01.06.631437Research output: Contribution to journal › Article › Academic
Open AccessFile26 Downloads (Pure) -
Platelets induce epithelial to mesenchymal transition in renal proximal tubular epithelial cells through TGF-β signaling pathway
Rustiasari, U. J., Uil, M., Zhang, X., Claessen, N., Butter, L., Florquin, S., Tammaro, A. & Roelofs, J. J. T. H., 1 Dec 2025, In: Molecular Medicine. 31, 1, 318.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile39 Downloads (Pure)
Prizes
Press/Media
Impacts
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