Projects per year
Personal profile
Research interests
Translational projects in non-alcoholic fatty liver disease, supported by Amsterdam UMC Fellowship 2018:
- innovation of multidisciplinary care
- ANCHOR: Amsterdam NAFLD-NASH cohort study @ AMC & VUmc
- LITMUS EU biobank (AMC: Dutch lead center)
- NILE project: prevalence and genetics of NAFLD in the multiethnic Helius cohort
- CRISTINA exercise intervention study in NAFLD
- lipid and liver pathways in rare metabolic diseases, with a focus on defects in lipophagy
- BARNARD: probiotics in mouse models of NAFLD
specialisation
Endocrinology and Metabolism; Vascular Medicine
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A translational step towards an auxiliary treatment for acid sphingomyelinase deficiency: Breaking the vicious cycle of sphingomyelin and cholesterol accumulation with recombinant high density lipoprotein.
Carla, H. H. (Staff), Holleboom, A. G. (Staff), Dallinga-thie, I. G. M. I. G. M. (Staff), van Kuilenburg, A. (Staff) & Voorink-moret, M. M. (Staff)
01/12/2016 → 30/11/2017
Project: Research
Research output
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Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021
Feng, G., Targher, G., Byrne, C. D., Yilmaz, Y., Wai-Sun Wong, V., Adithya Lesmana, C. R., Adams, L. A., Boursier, J., Papatheodoridis, G., el-Kassas, M., Méndez-Sánchez, N., Sookoian, S., Castera, L., Chan, W.-K., Ye, F., Treeprasertsuk, S., Cortez-Pinto, H., Yu, H. H., Kim, W. & Romero-Gómez, M. & 51 others, , 1 Mar 2025, In: JHEP Reports. 7, 3, 101271.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
Precision in Liver Diagnosis: Varied Accuracy Across Subgroups and the Need for Variable Thresholds in Diagnosis of MASLD
Vali, Y., van Dijk, A.-M., Lee, J., Boursier, J., Ratziu, V., Yunis, C., Schattenberg, J. R. M., Valenti, L., Gomez, M. R., Schuppan, D., Petta, S., Allison, M., Hartman, M. L., Porthan, K., Dufour, J.-F., Bugianesi, E., Gastadelli, A., Derdak, Z., Fournier-Poizat, C. & Shumbayawonda, E. & 11 others, , 1 Feb 2025, In: Liver international. 45, 2, e16240.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus) -
Randomised double-blind placebo-controlled trial protocol to evaluate the therapeutic efficacy of lyophilised faecal microbiota capsules amended with next-generation beneficial bacteria in individuals with metabolic dysfunction-associated steatohepatitis
Augustijn, Q. J. J., Grefhorst, A., de Groen, P., Wortelboer, K., Seegers, J. F. M. L., Gül, I. S., Suenaert, P., Verheij, J., de Vos, W. M., Herrema, H., Nieuwdorp, M. & Holleboom, A. G., 9 Jan 2025, In: BMJ open. 15, 1, e088290.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Anaerobutyricum soehngenii Reduces Hepatic Lipogenic Pathways and Increases Intestinal Gluconeogenic Gene Expression in Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) Mice
Mak, A. L., Augustijn, Q. J. J., Heymann, C. J. F., Havik, S., Verdoes, X., Rios-Morales, M., Bosmans, L. A., Verheij, J., Meijnikman, A. S., de Jonge, P. A., Herrema, H., de Vos, W. M., Nieuwdorp, M., Grefhorst, A. & Holleboom, A. G., 1 Mar 2024, In: International journal of molecular sciences. 25, 6, 3481.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)
The LITMUS Investigators, Jun 2024, In: Nature Metabolism. 6, 6, p. 1178-1196 19 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access47 Citations (Scopus)