Personal profile
Research interests
Development of different models along the airway and gut-brain axis:
1) Gut organoids and gut epithelial cultures
2) Human airway epithelial (HAE) cultures
3) Brain organoids
4) Blood-Brain Barrier
5) Immune cell co-culture with above models
Applied for elucidating the pathogenesis of several viruses:
1) Enterovirus D68 (EV-D68)
2) Enterovirus A71 (EV-A71)
3) Parechovirus A (PeV-A1 and PeV-A3)
4) SARS-CoV-2
5) RSV
6) CMV
7) HIV
Specialisation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 17 Partnerships for the Goals
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Effect of antivirals on clinical and lab-adapted human cytomegalovirus strains using induced pluripotent stem cell-derived human neural models
Mulder, L. A., Vieira da Sá, R., Korsten, J., Freeze, E., Schotting, A. J., Koen, G., Molenkamp, R., Kampen, J. V., Cornelissen, M., Zorgdrager, F., Wolthers, K. C., Pajkrt, D., Sridhar, A. & Calitz, C., 1 Sept 2025, In: Antiviral research. 241, 106233.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile17 Downloads (Pure) -
Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids
Capendale, P. E., Ambikan, A. T., García-Rodríguez, I., de Sá, R. V., Pajkrt, D., Wolthers, K. C., Neogi, U. & Sridhar, A., 1 Dec 2025, In: Cellular and molecular life sciences. 82, 1, 382.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile21 Downloads (Pure) -
Toward Personalized Medicine: The Effect of Treatment of Chronic Enterovirus Diarrhea in an Immunocompromised Patient and the Correlation With In Vitro Models
Moreni, G., Calitz, C., Koen, G., van Eijk, H., Johannesson, N., de Ruijter, J., Benschop, K. S. M., Cremer, J., Pajkrt, D., Sridhar, A., Peters, E. J. & Wolthers, K. C., 1 May 2025, In: Open Forum Infect. Dis.. 12, 5, p. ofaf212 ofaf212.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile27 Downloads (Pure) -
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models
García-Rodríguez, I., Moreni, G., Capendale, P. E., Mulder, L., Aknouch, I., Vieira de Sá, R., Johannesson, N., Freeze, E., van Eijk, H., Koen, G., Wolthers, K. C., Pajkrt, D., Sridhar, A. & Calitz, C., 1 Feb 2024, In: Antiviral research. 222, p. 105798 105798.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile28 Downloads (Pure) -
Exploring host-commensal-pathogen dynamics in cell line and organotypic human intestinal epithelial models
Nanlohy, N. M., Johannesson, N., Wijnands, L., Arroyo, L., de Wit, J., den Hartog, G., Wolthers, K. C., Sridhar, A. & Fuentes, S., 17 May 2024, In: iScience. 27, 5, 109771.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile23 Downloads (Pure)
Activities
- 1 Editorial activity
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Heliyon (Journal)
Sridhar, A. (Reviewer)
4 Mar 2024Activity: Publication peer-review and editorial work › Editorial activity
Prizes
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Proefdiervrij Venture Challenge 2023
Moreni, G. (Recipient), Garcia Rodriguez, I. (Recipient), Calitz, C. (Recipient), Pajkrt, D. (Recipient), Wolthers, K. (Recipient) & Sridhar, A. (Recipient), 24 Apr 2023
Prize › Societal
Press/Media
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De proefdiervrije toekomst krijgt al gestalte in het lab, met minibreinen en organen-op-een-chip
Sridhar, A., Wolthers, K. C. & Pajkrt, D.
21/01/2022
1 Media contribution
Press/Media: Press / Media
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LMtV Episode 56: Let‘s Meet the Virologist Adithya Sridhar
Sridhar, A., Wolthers, K. C. & Pajkrt, D.
20/09/2020
1 Media contribution
Press/Media: Press / Media